艾叶炭的化学成分研究  

Study on chemical compositions of Folium Artemisiae argyi carbonisatum

作　　者：谷乐 邵信婷 王雪钰 杨昭怡 段明华[1] 王烨 李勇[1] GU Le;SHAO Xinting;WANG Xueyu;YANG Zhaoyi;DUAN Minghua;WANG Ye;LI Yong(School of Pharmacy,Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]长春中医药大学药学院,长春130117

出　　处：《长春中医药大学学报》2022年第6期636-638,共3页Journal of Changchun University of Chinese Medicine

基　　金：吉林省中医药管理局(2020002)。

摘　　要：目的对艾叶炭中化学成分进行分离及结构鉴定,为炒炭存性理论以及艾叶炭质量标准的提升提供实验依据。方法采用回流提取法、CC(柱色谱)、HPLC及NMR对艾叶炭进行提取、分离纯化及化合物结构鉴定。结果从艾叶炭中分离出2个化合物,化合物1为槲皮素,化合物2为二十八烷醇。结论进一步验证了炒炭存性理论,为艾叶炭的活性研究及临床应用奠定基础。Objective To separate and identify the chemical compositions in Folium Artemisiae argyi carbonisatum,and to provide an experimental basis for the theory of drugs prepared as charcoals while with functions preserved and the improvement of quality standard of Folium Artemisiae argyi carbonisatum.Methods The chemical compositions of Folium Artemisiae argyi carbonisatum were extracted,purified and their structures were identified by the methods of reflux extraction,CC(column chromatography),HPLC and NMR.Results Two compounds,quercetin and octacosanol,were isolated from Folium Artemisiae argyi carbonisatum.Conclusion This study further verifies the theory of drugs prepared as charcoals while with functions preserved,and lays a foundation for the activity study and clinical application of Folium Artemisiae argyi carbonisatum.

关 键 词：艾叶炭 槲皮素 二十八烷醇 

分 类 号：R248.1[医药卫生—中医临床基础]