活血益气健脾方对肛瘘术后尿潴留患者的疗效观察及安全性评价  

Curative Effect Observation and Safety Evaluation of Huoxue Yiqi Jianpi Recipe in Patients with Urinary Retention after Anal Fistula Surgery

作　　者：吴清华 刘敦龙 WU Qinghua;LIU Dunlong(Jianli Hospital of Traditional Chinese Medicine,Jianli 433300,China;不详)

机构地区：[1]监利市中医医院,湖北监利433300 [2]监利市第四人民医院

出　　处：《中外医学研究》2022年第12期135-138,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析活血益气健脾方对肛瘘术后尿潴留患者的临床疗效及其安全性,旨在为临床用药提供参考。方法:选取监利市中医医院于2017年4月-2020年4月收治的96例肛瘘术后尿潴留患者为研究对象,根据随机数字表法分为治疗组(n=48)与对照组(n=48)。对照组给予甲硫酸新斯的明0.5 mg/次,1次/d,臀部肌肉注射;同时采取心理安慰、鼓励排尿、恢复平素排尿体位、下腹部冷热敷、听流水声刺激排尿等干预。治疗组在对照组基础上给予活血益气健脾方治疗。两组疗程均为3 d。比较两组疗效;比较术后自行排尿时间、排便时间、膀胱残留尿量及住院时间;比较两组术后6、24 h及术后3 d疼痛视觉模拟评分(VAS评分)及药物副作用的发生情况。结果:治疗组总有效率为93.75%,显著高于对照组的70.83%,差异有统计学意义(χ^(2)=10.952,P<0.05);治疗组自行排尿时间和排便时间均早于对照组,差异有统计学意义(t=-12.742、-10.875,P<0.05);治疗组术后3 d膀胱残留尿量少于对照组,住院时间短于对照组,差异有统计学意义(t=-20.577、-12.751,P<0.05);治疗组术后6、24 h及术后3 d的VAS评分显著低于对照组,差异有统计学意义(t=-7.658、-12.129、-21.366,P<0.05);两组均未发生严重药物副作用。结论:活血益气健脾方对肛瘘术后尿潴留患者的临床效果显著,且临床用药安全性良好。Objective:To analyze the clinical efficacy and safety of Huoxue Yiqi Jianpi Recipe for patients with urinary retention after anal fistula surgery,in order to provide reference for clinical medication.Method:A total of 96 patients with urinary retention after anal fistula surgery who were admitted to Jianli Hospital of Traditional Chinese Medicine from April 2017 to April 2020 were selected as the research subjects and divided into the treatment group(n=48)and the control group(n=48)according to the random number table.In the control group,Neostigmine Mesylate 0.5 mg/time,1 time/day was injected into hip muscles.At the same time,psychological comfort,encouraged urination,restored the normal urination position,cold and hot compress of the lower abdomen,and listening to the sound of running water to stimulate urination were performed.The treatment group was treated Huoxue Yiqi Jianpi Recipe on the basis of the control group.The course of treatment in both groups was 3 d.The efficacy of the two groups was compared.The spontaneous urination time,defecation time,residual urine in the bladder,and hospitalization time were compared between the two groups.The visual analogue scale(VAS)of pain at 6,24 h after operation and 3 d after operation and the incidence of drug side effects were compared between the two groups.Result:The total effective rate of treatment group was 93.75%,which was significantly higher than 70.83%of the control group,the difference was statistically significant(χ^(2)=10.952,P<0.05).The spontaneous urination time and defecation time in the treatment group were earlier than those in the control group,and the differences were statistically significant(t=-12.742,-10.875,P<0.05).The residual urine in the bladder 3 d after operation of the treatment group was less than that of the control group,and the hospitalization time was shorter than that of the control group,and the differences were statistically significant(t=-20.577,-12.751,P<0.05).The VAS scores of the treatment group at 6,24 h and 3 d after ope

关 键 词：活血益气健脾方 肛瘘 尿潴留 疗效 安全性 

分 类 号：R657.16[医药卫生—外科学]