房颤患者在RFCA术后应用药物维持与电复律对房颤晚期复发的影响对比  

Effects of Drug Maintenance and Electrical Cardioversion on Late Recurrence of Atrial Fibrillation in Patients with Atrial Fibrillation after RFCA

作　　者：钟耀棠 李诗成 李忠荣 程飞 ZHONG Yaotang;LI Shicheng;LI Zhongrong;CHENG Fei(Dongguan Songshanhu Central Hospital,Dongguan 523326,China;不详)

机构地区：[1]东莞市松山湖中心医院,广东东莞523326

出　　处：《中外医学研究》2022年第13期46-49,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究房颤患者在射频消融术(RFCA)术后采用药物维持与电复律对房颤晚期复发的影响。方法:选取2018年3月-2020年3月东莞市松山湖中心医院收治的房颤并采用RFCA治疗的患者93例,根据患者术后复律方法分为药物组49例和电复律组44例,药物组于术后3个月采用胺碘酮口服治疗,术后9个月房颤复发则调整胺碘酮用量予以改善,电复律组患者术后复发房颤采用电复律治疗。随访12个月,比较两组患者术后3~12个月房颤复发率、术前与术后3个月白细胞介素-6(IL-6),超敏C反应蛋白(hs-CRP)水平、左心室射血分数(LVEF)及左心房内经(LAD)。结果:(1)术后3~12个月药物组患者房颤复发率显著低于电复律组,差异有统计学意义(P<0.05);(2)术前两组IL-6及hs-CRP水平差异无统计学意义(P>0.05),术后3个月药物组IL-6及hs-CRP水平显著降低,且显著低于电复律组,差异有统计学意义(P<0.05);(3)术前两组LVEF及LAD对比差异无统计学意义(P>0.05),术后3个月两组LVEF均较术前显著提高,且LAD较术前显著降低,差异有统计学意义(P<0.05),但组间比较差异无统计学意义(P>0.05)。结论:胺碘酮维持治疗与术后复发房颤采用电复律治疗相比能有效降低房颤射频消融患者术后晚期房颤复发的发生率,降低体内炎症反应,改善心功能指标。Objective:To explore the effect of drug maintenance and electrical cardioversion on late recurrence of atrial fibrillation in patients with atrial fibrillation after radiofrequency ablation(RFCA).Method:A total of 93 patients with atrial fibrillation treated by RFCA in Dongguan Songshanhu Central Hospital from March 2018 to March 2020 were selected.According to the postoperative cardioversion method,the patients were divided into 49 cases in the drug group and 44 cases in the electrical cardioversion group.The drug group was treated with Amiodarone orally 3 months after operation,and the dosage of amiodarone was adjusted to improve the recurrence of atrial fibrillation 9 months after operation.The patients in the electrical cardioversion group were treated with electrical cardioversion.The patients were followed up for 12 months.The recurrence rate of atrial fibrillation at 3-12 months after operation,the levels of interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP),left ventricular ejection fraction(LVEF)and left atrial internal meridian(LAD)before operation and at 3 months after operation were compared between the two groups.Result:(1)The recurrence rate of atrial fibrillation in the drug group was significantly lower than that in the electric cardioversion group at 3-12 months after operation,and the difference was statistically significant(P<0.05).(2)There were no significant differences in the levels of IL-6 and hs-CRP between the two groups before operation(P>0.05),and the levels of IL-6 and hs-CRP in the drug group were significantly lower than those in the electric cardioversion group at 3 months after operation,and the differences were statistically significant(P<0.05).(3)LVEF and LAD in the two groups before operation were no significant differences between the two groups(P>0.05).Three months after operation,LVEF of the two groups was significantly higher than that before operation,and LAD was significantly lower than that before operation(P<0.05),but there were no significant differences be

关 键 词：房颤 射频消融 胺碘酮 电复律 

分 类 号：R541.75[医药卫生—心血管疾病]