双丹桃仁汤加减治疗不同证型肝硬化的效果  

Effect of Modified Shuangdan Taoren Decoction on Liver Cirrhosis with Different Syndrome Types

作　　者：唐少田 TANG Shaotian(Macheng Second People’s Hospital,Macheng 438307,China)

机构地区：[1]麻城市第二人民医院,湖北麻城438307

出　　处：《中外医学研究》2022年第13期127-131,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析双丹桃仁汤加减治疗不同证型肝硬化的效果。方法:回顾性收集2019年1月-2021年1月来麻城市第二人民医院治疗的100例肝硬化患者作为研究对象,根据中医辨证分为湿热型(试验组)和非湿热型(对照组),各50例,根据不同症状采用双丹桃仁汤加减药物治疗,对比两组疗效。结果:试验组总有效率高于对照组(P<0.05)。治疗前,试验组的TBIL高于对照组,差异有统计学意义(P<0.05);ALT、AST、ALB、PA、PT比较差异无统计学意义(P>0.05)。治疗后,两组ALT、AST均显著降低(P<0.05);试验组TBIL、PT明显降低,PA升高,试验组PA高于对照组(P<0.05)。对照组TBIL较治疗前降低,PT、PA升高,差异无统计学意义(P>0.05)。两组ALB治疗前后差异无统计学意义(P>0.05)。结论:双丹桃仁汤加减治疗湿热型肝硬化患者的整体疗效优于非湿热型患者,为临床选择适合肝硬化患者进行双丹桃仁汤加减治疗提供参考,值得推广。Objective:To analyze the effect of modified Shuangdan Taoren Decoction on liver cirrhosis with different syndrome types.Method:A total of 100 patients with liver cirrhosis treated in Macheng Second People’s Hospital from January 2019 to January 2021 were selected as the research object.According to the dialectics of traditional Chinese medicine,they were divided into damp heat type (experimental group) and non damp heat type (control group),with 50 cases in each group.According to different symptoms,add or subtract drug treatment on the basis of the Shuangdan Taoren Decoction,and the treatment effects of the two groups were compared.Result:The total effective rate of the experimental group was higher than that of the control group (P<0.05).Before treatment,TBIL in the experimental group was higher than that in the control group (P<0.05),and there were no significant differences in ALT,AST,ALB,PA and PT between two groups (P>0.05).After treatment,ALT and AST in the two groups decreased significantly (P<0.05).TBIL and PT decreased significantly and PA increased in the experimental group,and PA in the experimental group was higher than that in the control group (P<0.05).TBIL decreased and PT and PA increased in the control group,but the differences were not significant (P>0.05).There was no significant difference in ALB between the two groups before and after treatment (P>0.05).Conclusion:The overall efficacy of Shuangdan Taoren Decoction in the treatment of patients with damp heat cirrhosis is better than that of non damp heat patients.It provides a reference for clinical selection of patients with liver cirrhosis for the treatment of Shuangdan Taoren decoction,which is worthy of promotion.

关 键 词：肝硬化 双丹桃仁汤 中医证型 

分 类 号：R259[医药卫生—中西医结合]