Rotation of Biological Cells:Fundamentals and Applications  

作　　者：Tao Tang Yoichiroh Hosokawa Takeshi Hayakawa Yo Tanaka Weihua Li Ming Li Yaxiaer Yalikun 

机构地区：[1]Division of Materials Science,Nara Institute of Science and Technology,Nara 630-0192,Japan [2]Institute of Innovation for Future Society,Nagoya University,Aichi 464-8603,Japan [3]Department of Precision Mechanics,Faculty of Science and Engineering,Chuo University,Tokyo 112-8551,Japan [4]Graduate School of Frontier Biosciences,Osaka University,Osaka 565-0871,Japan [5]RIKEN Center for Biosystems Dynamics Research,Osaka 565-0871,Japan [6]School of Mechanical,Materials,Mechatronic,and Biomedical Engineering,University of Wollongong,Wollongong,NSW 2522,Australia [7]School of Engineering,Macquarie University,Sydney,NSW 2109,Australia

出　　处：《Engineering》2022年第3期110-126,共17页工程（英文）

基　　金：supported by JSPS Grant-in-Aid for Scientific Research(20K15151);Australian Research Council Discovery Projects(DP200102269);JSPS Core-to-Core program;Amada Foundation;White Rock Foundation。

摘　　要：Cell rotation is one of the most important techniques for cell manipulation in modern bioscience,as it not only permits cell observation from any arbitrary angle,but also simplifies the procedures for analyzing the mechanical properties of cells,characterizing cell physiology,and performing microsurgery.Numerous approaches have been reported for rotating cells in a wide range of academic and industrial applications.Among them,the most popular are micro-robot-based direct contact manipulation and field-based non-contact methods(e.g.,optical,magnetic,electric,acoustic,and hydrodynamic methods).This review first summarizes the fundamental mechanisms,merits,and demerits of these six main groups of approaches,and then discusses their differences and limitations in detail.We aim to bridge the gap between each method and illustrate the development progress,current advances,and prospects in the field of cell rotation.

关 键 词：Cell rotation Cell reorientation MICROMANIPULATION MICROFLUIDICS 

分 类 号：Q2-3[生物学—细胞生物学]