孕妇妊娠早期优生优育相关病原体的检测分析及意义  

Detection and Analysis of Prenatal and Postnatal Related Pathogens in Pregnant Women in Early Pregnancy and Its Significance

作　　者：王宜芹 王蒙 WANG Yiqin;WANG Meng(Medicine Management Service Section,Rizhao Center for Disease Control and Prevention,Rizhao,Shandong Province,276800 China;Department of Reproductive Medicine,Rizhao Maternal and Child Health Hospital,Rizhao,Shandong Province,276800 China)

机构地区：[1]日照市疾病预防控制中心药具管理服务科,山东日照276800 [2]日照市妇幼保健院生殖医学科,山东日照276800

出　　处：《系统医学》2022年第6期151-154,共4页Systems Medicine

摘　　要：目的探讨孕妇妊娠早期优生优育相关病原体的检测分析及意义。方法选取日照市妇幼保健院于2020年3月—2021年3月收治并建档的2033名妊娠早期孕妇为研究对象,将行相关病原体检测者1158名作为研究组,未行相关病原体检测者875名作为对照组,两组孕妇均完善孕期必需检测项目,给予对照组孕妇以常规孕期指导,研究组依检测结果给予孕妇针对性治疗与指导,统计研究组孕妇相关病原体的检测结果,比较两组孕妇的妊娠结局。结果经过检测分析后,1158名孕妇HBV、HCV、TP、TORCH的阳性检出率分别为3.97%、0.09%、0.60%、9.15%,未发现HIV病原体。研究组孕妇与胎儿或新生儿不良妊娠结局的发生率分别为2.68%、1.76%,较对照组的7.66%、4.73%均明显更低,差异有统计学意义(χ^(2)=26.942、14.640,P<0.05)。结论孕妇妊娠早期可能会存在各类感染性病原体,行乙肝、丙肝、艾滋病、梅毒、TORCH等相关病原体检测有利及时发病相关病原体,并采取有效的治疗与预防措施,保障母婴健康,实现优生优育。Objective To investigate the detection,analysis and significance of prenatal and postnatal related pathogens in pregnant women in early pregnancy.Methods A total of 2033 pregnant women in early pregnancy who were admitted and archived in Rizhao Maternal and Child Health Hospital from March 2020 to March 2021 were selected as the research objects.A total of 1158 pregnant women who were tested for related pathogens were selected as the study group,and 875 pregnant women who were not tested for related pathogens were selected as the control group.Pregnant women in both groups completed the necessary testing items during pregnancy,and the control group was given routine pregnancy guidance,while the study group was given targeted treatment and guidance according to the test results.The detection results of related pathogens in pregnant women in the study group were counted,and the pregnancy outcomes of the two groups of pregnant women were compared.Results After detection and analysis,the positive detection rates of HBV,HCV,TP and TORCH in 1158 pregnant women were 3.97%,0.09%,0.60%and 9.15%,respectively,and no HIV pathogen was found.The incidences of adverse pregnancy outcomes of pregnant women and fetuses or neonates in the study group were 2.68%and 1.76%,respectively,which were significantly lower than those in the control group,7.66%and 4.73%,and the difference was statistically significant(χ^(2)=26.942,14.640,P<0.05).Conclusion Pregnant women may have various infectious pathogens in early pregnancy.It is beneficial to detect related pathogens such as hepatitis B,hepatitis C,AIDS,syphilis,and TORCH in a timely manner,and take effective treatment and preventive measures to protect the health of mothers and infants,and achieve prenatal and postnatal care.

关 键 词：妊娠早期 优生优育 检测分析 孕期指导 妊娠结局 

分 类 号：R4[医药卫生—临床医学]