皮下注射胰岛素治疗基础上辅以维生素D辅助双C对高龄二胎GDM患者血糖水平及黎明现象发生率的影响  

Effects of Subcutaneous Insulin Injection Supplemented with Vitamin D Supplemented with Double C on Blood Glucose Level and the Incidence of Dawn Phenomenon in Elderly Patients with Second-born GDM

作　　者：刘桂英 LIU Guiying(Department of Obstetrics and Gynecology,Wuyishan Hospital of Traditional Chinese Medicine)

机构地区：[1]武夷山市中医院妇产科

出　　处：《糖尿病新世界》2022年第8期5-7,36,共4页Diabetes New World Magazine

摘　　要：目的 分析皮下注射胰岛素治疗基础上辅以维生素D辅助双C对高龄二胎妊娠期糖尿病(GDM)患者血糖水平及黎明现象发生率的影响。方法 选取2016年8月—2021年3月该院收治的65例高龄二胎GDM患者,随机分为对照组(33例)与研究组(32例)。对照组选择皮下注射胰岛素治疗,研究组则在皮下注射胰岛素治疗的同时,采用维生素D辅助双C治疗,比较临床疗效。结果 与治疗前相比,两组治疗后的空腹胰岛素(FINS)、糖化血红蛋白(HbA1c)、空腹血糖(FPG)、餐后2 h血糖(2 hPG)等血糖指标水平均明显降低,差异有统计学意义(P<0.05);与对照组相比,研究组治疗后的各项血糖指标水平降低幅度更加显著,差异有统计学意义(P<0.05)。与对照组相比,研究组的黎明现象、低血糖均明显减少,差异有统计学意义(P<0.05)。结论 高龄二胎GDM患者在接受皮下注射胰岛素治疗时,辅以维生素D辅助双C治疗能对其血糖水平进行有效控制,让黎明现象及低血糖发生风险明显降低,值得推广。Objective To analyze the effect of subcutaneous insulin injection supplemented with vitamin D and double C on blood glucose level and the incidence of dawn phenomenon in elderly patients with second-born gestational diabetes mellitus(GDM).Methods A total of 65 elderly patients with second-born GDM were treated in the hospital from August 2016 to March 2021 were selected,and were randomly divided into a control group(33 cases) and a study group(32 cases),the control group received subcutaneous insulin injection and the study group was treated with subcutaneous insulin injection and supplemented with vitamin D supplemented with double C treatment to compare the clinical efficacy.Results Compared with before treatment,the levels of fasting insulin(FINS),glycosylated hemoglobin(HbA1c),fasting blood glucose(FPG),2 h postprandial blood glucose(2 hPG) and other blood glucose indexes in the two groups after treatment were significantly decreased,and the difference was statistically significant(P<0.05).Moreover,compared with the control group,the levels of various blood glucose indexes in the study group decreased more significantly after treatment,and the difference was statistically significant(P<0.05).Compared with the control group,the dawn phenomenon and hypoglycemia in the study group were significantly reduced,and the difference was statistically significant(P<0.05).Conclusion When receiving subcutaneous insulin injection in elderly second-born GDM patients,supplemented with vitamin D and double C therapy can effectively control their blood glucose levels,and significantly reduce the risk of dawn phenomenon and hypoglycemia,which is worthy of promotion.

关 键 词：胰岛素 维生素D 双C治疗 高龄 二胎 妊娠期糖尿病 血糖水平 黎明现象 

分 类 号：R587.2[医药卫生—内分泌]