动态心电图心率变异性对糖尿病前期患者心血管不良事件的预测价值分析  

Analysis of the Predictive Value of Heart Rate Variability of Ambulatory Electrocardiogram for Cardiovascular Adverse Events in Patients with Prediabetes

作　　者：周秀菊[1] ZHOU Xiuju(Shengli Oilfield Central Hospital,Dongying,Shandong Province,257034 China)

机构地区：[1]胜利油田中心医院,山东东营257034

出　　处：《糖尿病新世界》2022年第8期12-15,共4页Diabetes New World Magazine

摘　　要：目的 探讨动态心电图心率变异性对糖尿病前期患者心血管不良事件的预测价值。方法 选取2020年1—12月该院收治糖尿病前期患者为分析对象,对其进行为期6个月的随访,122例糖尿病早期患者为观察组,122名健康体检者为对照组,对比两组实验室检查指标、心率变异性指标,并对比有无心血管不良事件患者心率变异性指标。结果 观察组空腹血糖(FPG)、餐后2 h血糖(2 hPG)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、HDL-C(高密度脂蛋白)水平优于对照组,差异有统计学意义(P<0.05),两组PNN50相比差异无统计学意义(P>0.05),观察组全部窦性心搏RR间期的标准差(SDNN)、相邻RR间期差值的均方根(rMSSD)、RR间期平均值标准差(SDANN)、总功率低于对照组,差异有统计学意义(P<0.05),随访6个月后,122例糖尿病前期患者中,发生心血管不良事件22例,发生率为18.03%(22/122);未发生心血管事件100例,未发生率为81.97%(100/122)。发生与未发生心血管不良事件患者的SDNN、总功率相比差异无统计学意义(P>0.05),发生患者的SDANN低于未发生心血管不良事件患者,差异有统计学意义(P<0.05),ROC曲线分析,结果显示:心血管事件累及发生率:SDANN≥71 ms组低于SDANN<71 ms组,差异有统计学意义(χ^(2)=4.545,P<0.05)。结论 动态心电图心率变异性指标对糖尿病前期患者心血管不良事件的发生具有一定预测价值,临床可以与其他指标联合使用。Objective To investigate the predictive value of heart rate variability(HRV) of ambulatory electrocardiogram in patients with prediabetes.Methods From January to December 2020,patients with prediabetes who were treated in the hospital were selected as the analysis objects,and they were followed up for 6 months.122 patients with early diabetes were the observation group,and 122 healthy subjects were the control group.The laboratory test indexes and heart rate variability indexes of the two groups were compared,and the heart rate variability indexes of patients with or without cardiovascular adverse events were compared.Results Fasting blood glucose(FPG),2 h postprandial blood glucose(2 hPG),total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL-C),high density lipoprotein(HDL-C) in the observation group the level was better than that of the control group,the difference was statistically significant(P<0.05).Compared with the PNN50 of the two groups,the difference was not statistically significant(P>0.05),the standard deviation of the RR intervals of all sinus beats(SDNN) and the root mean square of the difference between adjacent RR intervals(rMSSD) in the observation group,average standard deviation of RR interval(SDANN),and total power were lower than those in the control group,the difference was statistically significant(P<0.05).After 6 months of follow-up,among the 122 patients with prediabetes,22 had cardiovascular adverse events,with an incidence rate of 18.03%(22/122).No cardiovascular events occurred in 100 cases,and the non-incidence rate was 81.97%(100/122).Compared with the SDNN and total power of patients with and without adverse cardiovascular events,the difference was no statistically significant(P>0.05),the SDNN of patients with adverse cardiovascular events was lower than that of patients without adverse cardiovascular events,the difference was statistically significant(P<0.05).ROC curve analysis,the results showed:cardiovascular incidence of event involvement:SDANN≥71 ms group was low

关 键 词：动态心电图 心率变异性 糖尿病前期 心血管不良事件 

分 类 号：R587.1[医药卫生—内分泌]