妊娠期高血压疾病患者影响因素分析及对妊娠结局和生命质量的影响  

Analysis of Influencing Factors in Patients with Hypertensive Disorder Complicating Pregnancy and the Impact on Pregnancy Outcome and Quality of Life

作　　者：李晓燕 于姗姗[1] 王富荣 隋鹍 张彩芸 王丽[2] LI Xiao-yan;YU Shan-shan;WANG Fu-rong;SUI Kun;ZHANG Cai-yun;WANG Li(First Department of Obstetrics,Qingdao Municipal Hospital,Qingdao,Shandong,266000,China;Department of Obstetrics,Affiliated Hospital of Qingdao University,Qingdao,Shandong,266000,China)

机构地区：[1]青岛市市立医院产一科,山东青岛266000 [2]青岛大学附属医院产科,山东青岛266000

出　　处：《现代生物医学进展》2022年第8期1557-1561,共5页Progress in Modern Biomedicine

基　　金：山东省自然科学基金项目(ZR2016HM82)。

摘　　要：目的:分析妊娠期高血压疾病(HDCP)患者影响因素,并探讨HDCP对妊娠结局和生命质量的影响。方法:选取2018年1月~2021年1月我院收治的100例HDCP患者为HDCP组,另选取同期于我院产检的健康孕产妇100例为对照组。收集两组临床资料和妊娠结局,采用36项健康调查简表(SF-36)评价两组孕产妇的生命质量。单因素及多因素Logistic回归分析HDCP的影响因素。结果:单因素及多因素Logistics回归分析显示,年龄>35岁、孕前体质量指数≥28 kg/m;、焦虑/抑郁、高血压家族史为HDCP的独立危险因素,文化程度大专及以上、孕期规律补充钙剂为HDCP的独立保护因素(P<0.05)。与对照组比较,HDCP组剖宫产、新生儿窒息、产后出血、低体重儿、胎儿窘迫比例增加(P<0.05)。与对照组比较,HDCP组躯体功能、生理职能、一般健康状况、生命活力、社会功能、情感功能、精神健康评分降低,躯体疼痛评分增加(P<0.05)。结论:HDCP受多种因素影响,其发病会对患者妊娠结局和生命质量产生不良影响,临床应做好相关预防措施。Objective: To analyze the influencing factors of patients with hypertensive disorder complicating pregnancy(HDCP),and to explore the impact of HDCP on pregnancy outcome and quality of life. Methods: 100 patients with HDCP who were admitted to our hospital from January 2018 to January 2021 were selected as the HDCP group, and another healthy pregnant women who were antenatal care during the same period were selected as the control group. Clinical data and pregnancy outcomes were collected for both groups, and quality of life was evaluated using the Summary form of 36 health surveys scale(SF-36). Single and multivariate Logistic regression analysis was used to analyze the factors influencing of HDCP. Results: Single and multivariate Logistic regression analysis showed that age >35 years, pre-pregnancy body mass index ≥28 kg/m2, anxiety/depression and family history of hypertension were independent risk factors for HDCP, education of college or above and regular calcium supplementation during pregnancy were independent protective factors for HDCP(P<0.05). Compared with the control group, the proportion of cesarean section, neonatal asphyxia, postpartum hemorrhage, low birth weight infants and fetal distress in HDCP group increased(P<0.05). Compared with the control group, the SF-36scores of physical function, physiological function, general health status, vitality, social function, emotional function and mental health in HDCP group decreased, and the somatic pain score increased(P<0.05). Conclusion: HDCP is affected by many factors, and its incidence will have an adverse impact on pregnancy outcome and quality of life. Relevant preventive measures should be taken to improve pregnancy outcome and quality of life.

关 键 词：妊娠期高血压疾病 妊娠结局 生命质量 影响因素 

分 类 号：R714.252[医药卫生—妇产科学]