小颗粒自体脂肪移植在面部年轻化中的应用效果分析  

Analysis of the Application Effect of Small Particles of Autologous Fat Transplantation in Facial Rejuvenation

作　　者：张莉[1] 程新德[1] 朱云琳[1] 马红丽[1] 岳魁 朱婷婷[1] ZHANG Li;CHENG Xin-de;ZHU Yun-lin;MA Hong-li;YUE Kui;ZHU Ting-ting(Department of Plastic Surgery,Second Affiliated Hospital ofBengbu Medical College,Bengbu,Anhui,233030,China)

机构地区：[1]蚌埠医学院第二附属医院整形外科,安徽蚌埠233030

出　　处：《现代生物医学进展》2022年第7期1348-1351,1356,共5页Progress in Modern Biomedicine

基　　金：安徽省科技厅攻关项目(1704a0802162)。

摘　　要：目的:分析小颗粒自体脂肪移植应用于面部年轻化的临床疗效。方法:采用回顾性方法分析,选取本院自2018年1月-2020年12月收治的80例行面部年轻化患者的临床资料,随机分为对照组(40例,给予玻尿酸注射)与研究组(40例,给予小颗粒自体脂肪移植),比较两组患者的临床疗效、治疗前后的皮肤检测指标、鼻唇沟及下颌缘形态评分、术后并发症。结果:研究组患者优良率(83.33%)明显高于对照组(58.33%),有显著差异(P<0.05)。治疗3个月后,研究组患者的鼻唇沟、下颌缘形态评分、油脂、斑点评分均低于对照组,有显著差异(P<0.05)。研究组患者的皮肤水分、弹性评分高于对照组,有显著差异(P<0.05);治疗前TNF-α、hs-CRP水平组间差异无统计学意义(P>0.05),两组治疗后TNF-α、hs-CRP水平下降,且研究组治疗后TNF-α、hs-CRP水平低于对照组(P<0.05);两组患者并发症发生率经比较,无统计学意义(P>0.05)。结论:小颗粒自体脂肪移植用于面部年轻化可有效改善患者皮肤状态,促进患者皮肤水分、弹性的恢复,并改善油脂及斑点问题,且移植后造成的皮肤损伤较小,且有着较高安全性,值得临床应用。Objective:To analyze the clinical efficacy of small-particle autologous fat transplantation for facial rejuvenation.Methods:A retrospective analysis was used to select the clinical data of 80 patients with facial rejuvenation admitted in our hospital from January 2018 to December 2020,and randomly divide them into a control group(40 cases with Hyaluronic acid injection)and The study group(40 cases,using small granule autologous fat transplantation),compared the clinical efficacy,skin detection indexes before and after treatment,nasolabial fold and mandibular margin morphology scores,and postoperative complications between the two groups.Results:The excellent and good rate of patients in the study group(83.33%)was significantly higher than that of the control group(58.33%),and there was a significant difference(P<0.05).After 3 months of treatment,the nasolabial fold,mandibular margin morphology scores,grease and spots scores of the study group were lower than those of the control group,with significant differences(P<0.05).The skin moisture and elasticity scores of patients in the study group were higher than those in the control group,with significant differences(P<0.05);Before treatment,the levels of TNF-αand hs-CRP were not significantly different between the groups(P>0.05).After treatment,the levels of TNF-αand hs-CRP in the two groups decreased significantly,and the TNF-αand hs-CRP in the study group after treatment The level is lower than the control group(P<0.05);The complication rate of the two groups was not statistically significant after comparison(P>0.05).Conclusion:Small particles of autologous fat transplantation for facial rejuvenation can effectively improve the patient’s skin condition and promote the recovery of the patient’s skin moisture and elasticity.It also improves oil and spot problems,and the skin damage caused by transplantation is small,and it has high safety,which is worthy of clinical application.

关 键 词：面部年轻化 小颗粒自体脂肪移植 玻尿酸注射 整形 皮肤状态 

分 类 号：R622[医药卫生—整形外科] R826.8[医药卫生—外科学]