浙江省慢性病主要危险因素的归因疾病负担研究  

Burden of disease attributable to main risk factors of chronic diseases in Zhejiang Province

作　　者：张洁[1] 费方荣[1] 胡如英[1] 龚巍巍[1] 钟节鸣[1] ZHANG Jie;FEI Fangrong;HU Ruying;GONG Weiwei;ZHONG Jieming(Department of Non-communicable Diseases Control and Prevention,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China)

机构地区：[1]浙江省疾病预防控制中心慢性非传染性疾病预防控制所,浙江杭州310051

出　　处：《预防医学》2022年第6期541-546,554,共7页CHINA PREVENTIVE MEDICINE JOURNAL

摘　　要：目的了解2017年浙江省慢性病主要危险因素的归因疾病负担,为制定慢性病防控策略、降低疾病负担提供依据。方法利用2017年全球疾病负担研究(GBD 2017)数据,计算过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD)和伤残调整寿命年(DALY)等疾病负担指标,评价2017年浙江省不同性别、年龄人群归因于环境、代谢和行为等主要危险因素的慢性病疾病负担,并与1990年数据比较分析其变化趋势。结果2017年浙江省慢性病归因于使用烟草、不合理膳食和高血压的DALY率较高,分别为2807.08/10万、2724.72/10万和1878.69/10万;男性归因于使用烟草、不合理膳食和高血压的DALY率较高,分别为4764.77/10万、3297.00/10万和2076.92/10万;女性归因于不合理膳食、高血压和高血糖的DALY率较高,分别为2117.16/10万、1668.24/10万和1100.53/10万。15~<50岁人群慢性病归因于不合理膳食、药物滥用和使用烟草的DALY率较高,分别为759.29/10万、611.71/10万和605.37/10万;50~<70岁人群慢性病归因于使用烟草、不合理膳食和高血压的DALY率较高,分别为5528.37/10万、4628.18/10万和2757.78/10万。≥70岁人群慢性病归因于不合理膳食、使用烟草和高血压的DALY率较高,分别为16370.09/10万、15551.40/10万和14408.63/10万。与1990年比较,2017年高体质指数、饮酒、高血糖、高低密度脂蛋白胆固醇和药物滥用的DALY率上升,增幅分别为108.23%、48.59%、23.17%、17.64%和6.06%;空气污染、职业风险、不合理膳食和肾功能受损的DALY率下降,降幅分别为51.11%、44.81%、22.49%和19.83%;使用烟草和高血压的DALY率无明显变化。结论2017年浙江省归因于使用烟草、不合理膳食和高血压的慢性病疾病负担较重;高体质指数、饮酒和高血糖等行为和代谢相关危险因素的归因疾病负担较1990年升高。Objective To estimate the burden of disease(BOD)attributable to main risk factors of chronic diseases in Zhejiang Province in 2017,so as to provide the evidence for formulating the control strategy for chronic diseases and reducing BOD.Methods The results of the Global Burden of Disease Study 2017(GBD 2017)were extracted to evalu⁃ate years of life lost due to premature mortality(YLL),years lived with disability(YLD)and disability-adjusted life years(DALY).The gender-and age-specific BOD attributable to main risk factors of chronic diseases,including the environment,metabolism and behaviors,in Zhejiang Province in 2017 was estimated and compared with those in 1990.Results High DALY rates of chronic diseases were estimated attributable to tobacco use(2807.08/105),unreasonable diet(2724.72/105)and hypertension(1878.69/105)in Zhejiang Province in 2017,and high DALY rates of chronic dis⁃eases were estimated in men attributable to tobacco use(4764.77/105),unreasonable diet(3297.00/105)and hyperten⁃sion(2076.92/105),while high DALY rates of chronic diseases were estimated in women attributable to unreasonable diet(2117.16/105),hypertension(1668.24/105)and hyperglycemia(1100.53/105),respectively.Among individuals at ages of 15 to 49 years,high DALY rates of chronic diseases were estimated attributable to unreasonable diet(759.29/105),drug abuse(611.71/105)and tobacco use(605.37/105);among individuals at ages of 50 to 69 years,high DALY rates of chronic diseases were estimated attributable to tobacco use(5528.37/105),unreasonable diet(4628.18/105)and hy⁃pertension(2757.78/105);and among individuals at ages of 70 years and older,high DALY rates of chronic diseases were estimated attributable to unreasonable diet(16370.09/105),tobacco use(15551.40/105)and hypertension(14408.63/105).As compared to those in 1990,the DALY rates of chronic diseases attributable to high body mass in⁃dex,alcohol use,hyperglycemia,high low-density lipoprotein cholesterol and drug abuse increased by 108.23%,48.59%,23.17%,17.64%and 6.06%,a

关 键 词：慢性病 危险因素 疾病负担 伤残调整寿命年 

分 类 号：R195.4[医药卫生—卫生统计学]