右美托咪定和咪达唑仑应用于小儿静脉麻醉中的效果研究  

The Effect of Dexmedetomidine and Midazolam in Intravenous Anesthesia in Children

作　　者：李珍 LI Zhen(Department of Anesthesiology,Qinghai Women's and Children's Hospital,Xining,Qinghai Province,810000 China)

机构地区：[1]青海省妇女儿童医院手术麻醉科,青海西宁810000

出　　处：《中外医疗》2022年第10期58-61,共4页China & Foreign Medical Treatment

摘　　要：目的探讨右美托咪定和咪达唑仑在小儿静脉麻醉中的临床应用价值。方法方便选择该院2020年1月—2021年6月收治的126例行静脉麻醉患儿作为研究对象,按照计算机表法将患儿分组,各63例。对照组应用咪达唑仑,研究组应用右美托咪定麻醉,比较两组不同时间段心率、呼吸与血氧饱和度、镇静评分、疼痛评分与面罩与静脉穿刺接受率,比较两组患儿苏醒时间与入睡时间、手术后躁动情况与不良反应发生情况,比较两组患儿家属镇静满意率。结果研究组镇静评分高于对照组,疼痛评分低于对照组,差异有统计学意义(P<0.05)。研究组患儿家属镇静满意率为93.65%,高于对照组(80.95%),差异有统计学意义(P<0.05);研究组面罩与静脉穿刺接受率为95.24%,高于对照组79.37%,差异有统计学意义(P<0.05);研究组入睡时间低于对照组,差异有统计学意义(P<0.05);研究组手术后躁动率为6.35%,低于对照组20.63%,差异有统计学意义(P<0.05),研究组不良反应发生率为3.17%低于对照组的14.27%,差异有统计学意义(χ^(2)=4.881,P<0.05)。结论将右美托咪定应用在小儿静脉麻醉中应用的效果高于应用咪达唑仑的效果,镇静效果强,临床值得推广应用。Objective To investigate the clinical value of dexmedetomidine and midazolam in intravenous anesthesia in children.Methods A total of 126 children with intravenous anesthesia who were treated in the hospital from January 2020 to June 2021 were conveniently selected as the research objects,and the children were divided into groups according to the computer table method,with 63 cases in each group.The control group was given midazolam anesthesia,and the study group was given dexmedetomidine anesthesia.The heart rate,respiration and blood oxygen saturation,sedation score,pain score and sedation satisfaction rate,and mask and venipuncture rate were compared between the two groups at different time periods.The time of waking up and falling asleep,post-operative agitation and adverse reactions were compared between the two groups,compared the sedation satisfaction rates of the families of the two groups.Results The sedation score in the study group was higher than that in the control group,and the pain score in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The sedation satisfaction rate of children's family members in the study group was 93.65%,which was higher than that in the control group(80.95%),and the difference was statistically significant(P<0.05).The acceptance rate of mask and venipuncture in the study group was 95.24%,which was higher than that in the control group 79.37%,and the difference was statistically significant(P<0.05).The time to fall asleep in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The post-operative agitation rate in the study group was 6.35%,which was lower than 20.63%in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group was 3.17%,which was lower than 14.27%in the control group,the difference was statistically significant(χ^(2)=4.881,P<0.05).Conclusion The effect of dexmedetomi

关 键 词：右美托咪定 小儿静脉麻醉 咪达唑仑 

分 类 号：R726.1[医药卫生—儿科]