氟比洛芬酯联合右美托咪定对强化麻醉下甲状腺手术患者术后苏醒及疼痛的效果  

Effects of Flurbiprofen Axetil Combined with Dexmedetomidine on Postoperative Recovery and Pain in Patients Undergoing Thyroid Surgery under Intensive Anesthesia

作　　者：方锐伦 洪耀浩 吴书平 FANG Ruilun;HONG Yaohao;WU Shuping(Department of Anesthesiology,Jiangmen People's Hospital,Jiangmen,Guangdong Province,529000 China)

机构地区：[1]江门市人民医院麻醉科,广东江门529000

出　　处：《中外医疗》2022年第10期78-81,共4页China & Foreign Medical Treatment

摘　　要：目的分析氟比洛芬酯(FA)联合右美托咪定(DEX)对强化麻醉下甲状腺手术患者术后苏醒及疼痛的效果。方法方便选取2020年6月—2021年6月在该院进行甲状腺手术的72例患者,采用数字随机列表法分组,将其分为两组,每组36例,对照组采用右美托咪定药物麻醉,观察组在对照组基础上,增加氟比洛芬酯药物,对比两组患者苏醒时间和生命指标;对比两组不同时刻疼痛评分;对比两组患者麻醉满意度。结果对比两组患者苏醒时间,观察组为(6.74±0.85)min,对照组为(7.03±0.82)min,两组相比,差异无统计学意义(t=1.473,P>0.05)。对照组的MAP(70.50±7.26)mmHg,与观察组的(78.33±8.40)mmHg相比,前者低于后者,差异有统计学意义(t=4.231,P<0.05)。对照组的血氧饱和度(95.43±0.92)%低于观察组的(97.55±0.90)%,差异有统计学意义(t=9.883,P<0.05)。T1、T2、T3、T4不同时段,对照组的疼痛评分为(2.95±0.45)分、(2.95±0.44)分、(2.95±0.36)分、(2.95±0.31)分,均高于观察组的(2.45±0.39)分、(2.25±0.29)分、(1.45±0.39)分、(1.45±0.39)分,差异有统计学意义(t=5.038、7.970、16.957、18.065,P<0.05)。对照组的满意率77.78%,明显低于观察组的97.22%,差异有统计学意义(χ^(2)=4.571,P<0.05)。结论DEX与FA结合应用与甲状腺手术的麻醉中,患者在手术过程中生命体征维持稳定状态,手术之后疼痛评分减少,对苏醒时间不会产生影响,所以在临床上,能够得到推广和应用。Objective To analyze the effect of flurbiprofen axetil(FA)combined with dexmedetomidine(DEX)on postoperative recovery and pain in patients undergoing thyroid surgery under intensive anesthesia.Methods A total of 72 patients who underwent thyroid surgery in the hospital from June 2020 to June 2021 were conveniently selected.They were divided into two groups with 36 cases in each group.The control group was anesthetized with dexmedetomidine,while the observation group was given flurbiprofen axetil on the basis of the control group.The recovery time and vital indicators of the two groups were compared;the pain scores at different times were compared between the two groups.The anesthesia satisfaction of the two groups was compared.Results Comparing the wake-up time between the two groups,the observation group was(6.74±0.85)min,and the control group was(7.03±0.82)min,and the difference between the two groups was small,the difference was not statistically significant(t=1.473,P>0.05).The MAP of the control group was(70.50±7.26)mmHg,which was lower than that of the observation group(78.33±8.40)mmHg,the difference was statistically significant(t=4.231,P<0.05).The blood oxygen saturation of the control group was(95.43±0.92)%lower than that of the observation group(97.55±0.90)%,the difference was statistically significant(t=9.883,P<0.05).The pain scores of the control group were(2.95±0.45)points,(2.95±0.44)points,(2.95±0.36)points,and(2.95±0.31)points in different time periods of T1,T2,T3,and T4 were higher than those of the observation group(2.45±0.39)points,(2.25±0.29)points,(1.45±0.39)points,and(1.45±0.39)points,and the differences was statistically significant(t=5.038,7.970,16.957,18.065,P<0.05).The satisfaction rate of the control group was 77.78%,which was significantly lower than 97.22% of the observation group,and the difference was statistically significant(χ^(2)=4.571,P<0.05).Conclusion In the combined application of DEX and FA and anesthesia for thyroid surgery,the patient's vital signs remain stab

关 键 词：氟比洛芬酯 右美托咪定 强化麻醉下甲状腺手术患者 麻醉效果 

分 类 号：R5[医药卫生—内科学]