体外冲击波治疗纤维肌痛综合征患者的安全性及有效性分析  

Analysis of Safety and Efficacy of Extracorporeal Shock Wave in the Treatment of Patients with Fibromyalgia Syndrome

作　　者：肖子振 贺涛[1] 王卫平[1] 伍国芳[1] XIAO Zizhen;HE Tao;WANG Weiping;WU Guofang(Department of Anesthesiology,Loudi Central Hospital,Loudi,Hunan Province,417000 China)

机构地区：[1]娄底市中心医院麻醉科,湖南娄底417000

出　　处：《中外医疗》2022年第8期18-23,共6页China & Foreign Medical Treatment

基　　金：娄底市中心医院课题(Y2020-14)。

摘　　要：目的观察体外冲击波治疗纤维肌痛综合征患者的安全性及临床有效性。方法便利选取2020年5月—2021年5月在娄底市中心医院疼痛中心门诊就诊的符合纤维肌痛综合征诊断标准的患者60例作为研究对象,按照随机数表法分为观察组(n=30)和对照组(n=30)。对观察组的患者在药物治疗的基础上给予体外冲击波治疗,对对照组的患者在药物治疗的基础上给予体外冲击波模拟安慰治疗。对两组患者进行持续12周的治疗。比较两组患者的治疗总有效率,对比两组患者治疗前,治疗后15、30、90 d的视觉模拟评分(VAS),比较两组患者治疗前后压痛点个数和匹兹堡睡眠质量指数(PSQI)、汉密尔顿抑郁量表评分(HAMD),比较两组患者治疗过程中的不良反应发生率。结果观察组患者的治疗总有效率显著高于对照组(80.00%vs 46.67%),差异有统计学意义(χ^(2)=7.177,P<0.05)。治疗前,两组患者VAS评分对比[(6.42±1.02)分vs(6.45±1.05)分],差异无统计学意义(t=0.112,P>0.05);治疗后15 d[(5.13±0.87)分vs(6.34±0.92)分]、治疗后30 d[(4.25±0.65)分vs(5.58±0.84)分]、治疗后90 d[(2.54±0.32)分vs(4.21±0.54)分],观察组的VAS评分均显著低于对照组,差异有统计学意义(t=5.234、6.859、14.572,P<0.05)。治疗前,两组患者的压痛点数对比[(14.23±5.23)点vs(14.56±4.89)点],差异无统计学意义(t=0.252,P>0.05);治疗后,观察组患者的压痛点数显著少于对照组[(6.54±3.24)点vs(10.25±4.21)点],差异有统计学意义(t=3.825,P<0.05)。治疗前,两组患者的匹兹堡睡眠质量指数对比[(18.52±4.52)分vs(18.67±5.84)分],差异无统计学意义(t=0.111,P>0.05);治疗后,观察组患者的匹兹堡睡眠质量指数显著低于对照组[(7.45±2.45)分vs(12.58±4.21)分],差异有统计学意义(t=5.768,P<0.05)。治疗前,两组患者HAMD评分对比[(16.54±4.32)分vs(16.84±5.23)分],差异无统计学意义(t=0.240,P>0.05);治疗后,观察组患者的HAMD评分显著低于对Objective To observe the safety and clinical efficacy of extracorporeal shock wave in the treatment of patients with fibromyalgia syndrome.Methods A total of 60 patients who met the diagnostic criteria of fibromyalgia syndrome in the outpatient department of the Pain Center of Loudi Central Hospital from May 2020 to May 2021 were conveniently selected as the research objects.According to the method of random number table,they were divided into observation group(n=30)and control group(n=30).The patients in the observation group were given extracorporeal shock wave therapy on the basis of drug treatment,and the patients in the control group were given extracorporeal shock wave simulation placebo treatment on the basis of drug treatment.The two groups of patients were treated for 12 weeks.The total effective rates of the two groups of patients were compared,and the visual analogue scale(VAS)was compared between the two groups before treatment,15 d,30 d,90 d,after treatment.The number of tender points,pittsburgh sleep quality index(PSQI)and hamilton depression Scale(HAMD)were compared between the two groups before and after treatment.The incidence of adverse reactions in the two groups of patients during treatment was compared.Results The total effective rate of the observation group was significantly higher than that of the control group(80.00%vs 46.67%),the difference was statistically significant(χ^(2)=7.177,P<0.05).Before treatment,there was no significant difference in VAS score between the two groups[(6.42±1.02)points vs(6.45±1.05)points](t=0.112,P>0.05);15 d after treatment[(5.13±0.87)points vs(6.34±0.92)points],30 d after treatment[(4.25±0.65)points vs(5.58±0.84)points],and 90 d after treatment[(2.54±0.32)points vs(4.21±0.54)points],the VAS scores of the observation group were significantly lower than those of the control group,the difference was statistically significant(t=5.234,6.859,14.572,P<0.05).Before treatment,there was no significant difference in the number of tenderness points between the t

关 键 词：体外冲击波 纤维肌痛综合征 疼痛 抑郁 睡眠质量 

分 类 号：R5[医药卫生—内科学]