出 处:《中外医疗》2022年第8期37-41,共5页China & Foreign Medical Treatment
摘 要:目的研究改良式B-Lynch缝合术联合卡前列素氨丁三醇治疗中央性前置胎盘患者产后出血的临床效果。方法方便选取2020年1月—2021年1月在该院住院治疗的82例中央性前置胎盘患者为研究对象,随机分为对照组(41例)与研究组(41例)。对照组行缩宫素联合8字缝合法治疗,研究组行改良B-Lynch缝合术联合卡前列素氨丁三醇治疗;比较两组治疗效果。结果研究组手术结束即刻D-二聚体水平(3.39±0.35)mg/L、纤维蛋白原水平(4.41±0.35)g/L,术后24 h D-二聚体水平(1.19±0.18)mg/L、纤维蛋白原水平(3.10±0.28)g/L均低于对照组,差异有统计学意义(t=11.478、16.618、22.301、15.555,P<0.05);研究组术中出血量(1539.63±229.57)mL、术后24 h出血量(199.04±21.36)mL少于对照组,止血时间(8.03±0.98)min、下床活动时间(2.11±0.29)d及住院时间(5.76±0.68)d短于对照组,差异有统计学意义(t=6.201、8.269、15.246、41.276、15.199,P<0.05);研究组术后总有效率97.56%高于对照组78.05%,差异有统计学意义(χ^(2)=7.289,P<0.05);研究组术后并发症总发生率低于对照组(2.44%<19.51%),差异有统计学意义(χ^(2)=4.493,P<0.05)。结论改良式B-Lynch缝合术联合卡前列素氨丁三醇治疗中央性前置胎盘患者产后出血的临床效果显著,可有效改善患者凝血功能,减少出血量及并发症,促使其术后快速恢复。Objective To study the clinical effect of modified B-lynch suture combined with carboprost tromethamine in the treatment of postpartum hemorrhage in patients with central placenta previa.Methods A total of 82 patients with central placenta previa were conveniently selected as the research objects.They were all hospitalized in the hospital from January 2020 to January 2021.They were randomly divided into the control group(41 cases)and the study group(41 cases).The control group was treated with oxytocin combined with figure 8 suture,and the study group was treated with modified B-lynch suture combined with carboprost tromethamine;the therapeutic effects of the two groups were compared.Results Immediately after the operation,the D-dimer level in the study group was(3.39±0.35)mg/L,and the fibrinogen level was(4.41±0.35)g/L,the D-dimer level(1.19±0.18)mg/L and fibrinogen level(3.10±0.28)g/L at 24 h after operation were lower than those in the control group,the difference was statistically significant(t=11.478,16.618,22.301,15.555,P<0.05).The intraoperative blood loss in the study group was(1539.63±229.57)mL and the blood loss at 24 h after surgery(199.04±21.36)mL was less than that in the control group;the hemostasis time(8.03±0.98)min,the time to get out of bed(2.11±0.29)d and the hospital stay(5.76±0.68)d were shorter than those of the control group,and the differences were statistically significant(t=6.201,8.269,15.246,41.276,15.199,P<0.05).The total effective rate in the study group was 97.56%higher than that in the control group,78.05%,the difference was statistically significant(χ^(2)=7.289,P<0.05).The total incidence of postoperative complications in the study group was lower than that in the control group(2.44%<19.51%),and the difference was statistically significant(χ^(2)=4.493,P<0.05).Conclusion Improved B-lynch suture combined with carboprost tromethamine has significant clinical effect in the treatment of postpartum hemorrhage in patients with central placenta previa,which can effectively impro
关 键 词:缩宫素 改良式B-LYNCH缝合术 卡前列素氨丁三醇 中央性前置胎盘 产后出血
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