射频消融联合经导管肝动脉栓塞化疗对肝癌的疗效研究  

Efficacy of Radiofrequency Ablation Combined with Transcatheter Hepatic Arterial Chemoembolization for Hepatocellular Carcinoma

作　　者：杨勇进 YANG Yongjin(The Eighth People's Hospital of Jinan City,Jinan,Shandong Province,271104 China)

机构地区：[1]济南市第八人民医院,山东济南271104

出　　处：《中外医疗》2022年第8期46-49,共4页China & Foreign Medical Treatment

摘　　要：目的研究分析肝癌治疗中,射频消融、经导管肝动脉栓塞化疗联合的临床疗效。方法便利选取2018年1月—2019年5月164例肝癌患者为研究对象,以单双号方式分组,对照组(82例)采取经导管肝动脉栓塞化疗,研究组(82例)增加射频消融治疗,对比两组肝功能、肿瘤坏死率、复发率、生存率、并发症发生情况等。结果治疗后,研究组肝功能指标总胆红素、谷丙转氨酶、谷草转氨酶分别为(25.44±5.31)μmol/L、(59.89±10.12)U/L、(42.65±4.73)U/L,优于对照组的(38.45±9.06)μmol/L、(74.33±12.90)U/L、(50.86±6.28)U/L,差异有统计学意义(t=11.218、7.975、9.456,P<0.05)。研究组肿瘤坏死率、复发率、生存率。分别为96.34%、8.53%、47.56%较对照组75.60%、19.51%、31.70%更为理想,差异有统计学意义(χ^(2)=14.614、4.096、4.307,P<0.05)。对照并发症总发生率为组23.17%、研究组为21.95%,差异无统计学意义(χ^(2)=0.035,P>0.05)。结论肝癌治疗中采取射频消融、经导管肝动脉栓塞化疗联合治疗,能够对患者病情做到有效控制,提高其生存率,并且能够极大程度改善患者预后,疾病治疗效果佳。Objective To study and analyze the clinical efficacy of radiofrequency ablation combined with transcatheter arterial chemoembolization in the treatment of liver cancer.Methods 164 patients with liver cancer from January 2018 to may 2019 were conveniently selected as the research objects and divided into single and double numbers.The control group(82 cases)received transcatheter hepatic artery chemoembolization,and the study group(82 cases)increased radiofrequency ablation.The liver function,tumor necrosis rate,recurrence rate,survival rate and complications of the two groups were compared.Results After treatment,the total bilirubin,alanine aminotransferase and aspartate aminotransferase of the study group were(25.44±5.31)μmol/L,(59.89±10.12)U/L,(42.65±4.73)U/L,respectively,which was better than that of the control group(38.45±9.06)μmol/L,(74.33±12.90)U/L,(50.86±6.28)U/L,the difference was statistically significant(t=11.218,7.975,9.456,P<0.05).The tumor necrosis rate,recurrence rate and survival rate in the study group were 96.34%,8.53%and 47.56%,respectively,which was more ideal than 75.60%,19.51%and 31.70%in the control group,the difference was statistically significant(χ^(2)=14.614,4.096,4.307,P<0.05).The total incidence of complications was 23.17%in the control group and 21.95%in the study group,and the difference was not statistically significant(χ^(2)=0.034,P>0.05).Conclusion Radiofrequency ablation combined with transcatheter arterial chemoembolization in the treatment of liver cancer can effectively control the patient's condition and improve the survival rate.And it can greatly improve the prognosis of patients,and the disease treatment effect is good.

关 键 词：射频消融 经导管肝动脉栓塞化疗 肝癌 疗效 

分 类 号：R5[医药卫生—内科学]