应用影像组学鉴别儿童颞骨胆脂瘤与朗格汉斯组织细胞增生症  

Radiomics in Differentiating Temporal Bone Cholesteatoma from Langerhans Histiocytosis in Children

作　　者：刘静[1,2] 段博[1,2] 钟水军 乔中伟[1,2] 许政敏 LIU Jing;DUAN Bo;ZHONG Shuijun;QIAO Zhongwei;XU Zhengmin(Department of Otorhinolaryngology,Jiaxing Maternal and Child Health Hospital;Department of Otorhinolaryngology head and Neck Surgery,Fudan University Children’s Hospital,Shanghai)

机构地区：[1]嘉兴市妇幼保健院耳鼻咽喉科 [2]上海复旦大学附属儿科医院耳鼻咽喉头颈外科

出　　处：《中华耳科学杂志》2022年第3期509-512,共4页Chinese Journal of Otology

摘　　要：目的比较颞骨胆脂瘤和颞骨朗格汉斯组织细胞增生症影像组学特征,为早期确诊提供参考。方法回顾性分析2016年1月至2020年12月在复旦大学附属儿科医院治疗的颞骨胆脂瘤及颞骨朗格汉斯组织细胞增生症患儿的临床资料,利用影像组学特征分析17例(17耳)颞骨胆脂瘤和13例(13耳)颞骨朗格汉斯组织细胞增生症的患儿影像学资料。结果有3种相关系数较大的影像组学稳定特征:相关性的信息量度(Informational Measure of Correlation,IMC),粗度(Coarseness),小区域重点(SmallAreaEmphasis,SAE)。朗格汉斯组织细胞增生症CT体素IMC和胆脂瘤有明显区别。朗格汉斯组织细胞增生症的Coarseness、SAE要明显高于胆脂瘤。结论影像组学特征分析可以作为颞骨病变鉴别诊断的重要辅助手段。IMC,Coarseness,SAE可以作为鉴别颞骨胆脂瘤和颞骨朗格汉斯组织细胞增生症的重要特征,为早期诊断提供重要线索。Objective To compare Radiomic features of temporal bone cholesteatoma and temporal bone Langerhans histiocytosis,so as to improve early diagnosis.Methods Clinical data of children with temporal bone cholesteatoma and temporal bone Langerhans histiocytosis treated at the Fudan University Children's Hospital from January 2016 to December 2020 were retrospectively analyzed using radiomics,including 17 cases(17 ears)of temporal bone cholesteatoma and 13 cases(13 ears)of temporal bone Langerhans histiocytosis.Results The three consistent radiomics features with high levels of correlation were Informational Measure of Correlation(IMC),Coarseness and Small Area Emphasis(SAE).CT voxel IMC in Langerhans histiocytosis was significantly different from that in cholesteatoma.Thickness and SAE in Langerhans histiocytosis greater than in cholesteatoma.Conclusion Radiomic feature analysis can be used as an important tool in the differential diagnosis of temporal bone lesions.IMC,coarseness and SAE can be used as important features for distinguishing temporal bone cholesteatoma and temporal bone Langerhans histiocytosis and as important clues for early diagnosis.

关 键 词：颞骨胆脂瘤 颞骨朗格汉斯组织细胞增生症 影像组学 儿童 

分 类 号：R764[医药卫生—耳鼻咽喉科]