菊花钩藤汤加减治疗阴虚阳亢型围绝经期综合征的临床分析  

Clinical Analysis of Juhua Gouteng Decoction in the Treatment of Perimenopausal Syndrome of Yin Deficiency and Yang Hyperactivity

作　　者：林春 LIN Chun(Department of Gynecology,Jiexi Hospital of Traditional Chinese Medicine,Jieyang,Guangdong Province,515400 China)

机构地区：[1]揭西县中医医院妇科,广东揭阳515400

出　　处：《中外医疗》2022年第12期9-13,共5页China & Foreign Medical Treatment

摘　　要：目的研究菊花钩藤汤加减运用于阴虚阳亢型围绝经期综合征中的价值。方法方便选取该院2018年2月—2021年2月收治的88例围绝经期综合征(阴虚阳亢型)患者为研究对象,按随机数表法分成两组,各44例。研究组服用菊花钩藤汤加减,对照组使用常规西药治疗,对两组总有效率进行评价,用药前后评价两组临床症状积分、生活质量(QOL)评分,同时测定两组性激素[促黄体生成激素(LH)、促卵泡生成激素(FSH)、雌二醇(E_(2))]、双侧股骨头密度、腰椎密度、子宫内膜厚度,比较两组用药结果。结果研究组总有效率86.36%高于对照组68.18%,差异有统计学意义(χ^(2)=4.141,P<0.05)。用药前,两组临床症状积分比较,差异无统计学意义(P>0.05);用药后,研究组症状积分低于对照组,差异有统计学意义(P<0.05)。用药前,两组性激素比较,差异无统计学意义(P>0.05);用药后,研究组LH、FSH、E_(2)优于对照组,差异有统计学意义(P<0.05)。用药前,两组双侧股骨头密度、腰椎密度、子宫内膜厚度比较,差异无统计学意义(P>0.05);用药后,研究组双侧股骨头密度、腰椎密度高出对照组,但子宫内膜厚度低于对照组,差异有统计学意义(P<0.05)。用药前,两组QOL评分比较,差异无统计学意义(P>0.05);用药后,研究组QOL评分高于对照组,差异有统计学意义(P<0.05)。结论菊花钩藤汤加减的效果显著,可促进患者症状快速消失,并改善性激素,提升骨密度,缩小子宫内膜厚度,患者生活质量明显提升,值得推广。Objective To study the value of modified Juhua Gouteng decoction in perimenopausal syndrome of Yin deficiency and Yang hyperactivity.Methods A total of 88 patients with perimenopausal syndrome(Yin deficiency and Yang hyperactivity type)admitted to the hospital from February 2018 to February 2021 were conveniently selected as the research objects,and divided into two groups according to the random number table method,with 44 cases in each group.The study group took the modified Juhua Gouteng decoction,and the control group was treated with conventional western medicine.The total effective rate of the two groups was evaluated,and the clinical symptom scores and quality of life(QOL)scores of the two groups were evaluated before and after treatment.The sex hormones[luteinizing hormone(LH),follicle-stimulating hormone(FSH),estradiol(E_(2))],bilateral femoral head density,lumbar spine density,and endometrial thickness were measured at the same time.The results of the two groups were compared.Results The total effective rate of the study group was 86.36%higher than that of the control group 68.18%,and the difference was statistically significant(χ^(2)=4.141,P<0.05).Before medication,there was no statistically significant difference in clinical symptom scores between the two groups(P>0.05).After treatment,the score of the clinical symptom study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the two groups of sex hormones(P>0.05).After treatment,LH,FSH and E_(2) in the study group were better than those in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in bilateral femoral head density,lumbar spine density and endometrial thickness between the two groups(P>0.05).After treatment,the bilateral femoral head density and lumbar vertebra density in the study group were higher than those in the control gr

关 键 词：围绝经期综合征 菊花钩藤汤加减 尼尔雌醇 阴虚阳亢型 

分 类 号：R711[医药卫生—妇产科学]