人类辅助生殖技术中评估胚胎发育潜能的四种方法  

Four methods for evaluating embryo developmental potential in human assisted reproductive technology

作　　者：王浩原 王崴然 白春梅 刘甜甜[1] 土增荣[1] WANG Hao-yuan;WANG Wei-ran;BAI Chun-mei;LIU Tian-tian;TU Zeng-rong(Shanxi Medical University,Taiyuan 030000)

机构地区：[1]山西医科大学,太原030000

出　　处：《生殖医学杂志》2022年第6期850-856,共7页Journal of Reproductive Medicine

摘　　要：近年来,辅助生殖技术(ART)取得了长足的发展,IVF-ET的抱婴率也呈现不断增加的趋势。评估胚胎发育潜能方法的精准性,对于预测妊娠结局有着重要意义。目前,评估胚胎发育潜能的方法,包括胚胎形态学观察、胚胎活检、囊胚液检测、胚胎培养基检测,本文将对以上4种用于评估胚胎发育潜能方法的利弊、干扰因素及安全性进行综述,为之后技术革新和临床应用提供参考。In recent years,assisted reproductive technology(ART)has made great progress and development.Live birth rate of IVF-ET shows an increasing trend.Accurate assessment of embryo developmental potential is of great significance for predicting pregnancy outcome.At present,the methods for evaluating embryo developmental potentiality includes embryo morphology observation,embryo biopsy,blastocyst fluid detection and embryo culture medium detection.This paper reviews the advantages,disadvantages,interference factors and safety of the above four methods for evaluating embryonic development potential,so as to provide reference for technical innovation and clinical application in the future.

关 键 词：胚胎发育潜能 胚胎植入前遗传学检查 形态学 囊胚液 胚胎培养基 

分 类 号：R714.8[医药卫生—妇产科学]