Disseminated herpes simplex infection induced hepatitis during pregnancy mimicking HELLP syndrome,a diagnostic challenge  

作　　者：Hassam Ali Shruthi Kumar Mary-Kate Kratzer Josef Kinderwater 

机构地区：[1]Department of Internal Medicine,East Carolina University/Vidant Medical Center,Greenville,NC

出　　处：《Infectious Medicine》2022年第1期67-72,共6页感染医学（英文）

摘　　要：The disseminated herpes simplex virus 2(HSV-2)carries a high mortality rate in pregnant women if left unrec-ognized.It often presents as unrelieved fever and hepatitis.Diagnosis is challenging due to vague symptoms and potential overlap with other conditions.Pregnancy is a risk factor as it conforms to a partially immunocompro-mised state.Dissemination to the brain could be devastating,and the treatment requires intravenous antivirals like acyclovir.Fetal outcomes are variable based on previous case reports.We present a case of young female gravida 1 para 1 who presented with disseminated HSV infection mimicking HELLP(Hemolysis,Elevated Liver enzymes,and Low Platelets)syndrome.She responded well to intravenous acyclovir,and the fetus had a viable outcome at the 26th week of gestation.Early diagnosis can prevent progression to fulminant liver failure and the need for a liver transplant.

关 键 词：Disseminated herpes simplex virus 2 PREGNANCY Infectious complications of pregnancy Hsv-2 infection Hepatitis in pregnancy 

分 类 号：R71[医药卫生—妇产科学]