少菌型麻风治疗后麻风反应合并大疱性类天疱疮1例  

A case report of leprosy reaction combined with bullous pemphigoid after treatment of paucibacillary leprosy

作　　者：谭又吉[1] 汪萌萌[1] 沈国丽[1] 王燕敏 TAN Youji;WANG Mengmeng;SHEN Guoli;WANG Yanmin(Institute of Dermatology of Zhejiang Province,Deqing,Zhejiang 313200,China)

机构地区：[1]浙江省皮肤病防治研究所,浙江德清313200

出　　处：《上海预防医学》2022年第4期376-377,387,共3页Shanghai Journal of Preventive Medicine

摘　　要：【目的】探讨少菌型麻风治疗后发生麻风反应神经炎合并大疱性类天疱疮的临床特点。【方法】对1例麻风治愈者在出现麻风反应后合并发生类天疱疮的治疗进行分析。【结果】患者接受麻风规范治疗后5年,无明显诱因情况下出现四肢红斑、水泡,并进行性加重。结合临床诊断及病理检查诊断为类天疱疮,给予激素治疗麻风反应以及抗免疫治疗,同时对症支持治疗。【结论】麻风反应与类天疱疮均与机体免疫力有关,但是两者同时发生的情况较为少见,所以在临床过程中要高度重视,做到早发现、早诊断、早治疗,避免对患者造成更大伤害。[Objective] To investigate the clinical characteristics of leprosy-related neuritis with bullous pemphigoid after treatment of paucibacillary leprosy.[Methods] The treatment of leprosy reaction combined with bullous pemphigoid of a cured case of leprosy was analysed.[Results]Five years after standard treatment for leprosy,erythema and vesicles appeared in the limbs without obvious inducement,and the disease became more and more severe. With clinical diagnosis and pathological examination,pemphigoid was confirmed,and the patients were given hormone treatment for leprosy reaction and anti-immunotherapy,as well as symptomatic supportive treatment.[Conclusion]Leprosy reaction and pemphigoid are both related to immunity,but the occurrence of both at the same time is relatively rare,so in the clinical process we should attach great importance to early detection,early diagnosis and prompt treatment to prevent further harm to the patient.

关 键 词：少菌型麻风 麻风反应 类天疱疮 神经炎 

分 类 号：R275.2[医药卫生—中医皮科]