开喉剑喷雾剂联合头孢曲松治疗急性化脓性扁桃体炎患儿临床研究  

Clinical Study on Kaihoujian Sprays Combined with Cefatriaxone for Acute Suppurative Tonsillitis in Children

作　　者：李旦阳 LI Danyang

机构地区：[1]余姚市妇幼保健院儿科,浙江余姚315408

出　　处：《新中医》2022年第8期129-132,共4页New Chinese Medicine

摘　　要：目的:观察开喉剑喷雾剂联合注射用头孢曲松钠治疗急性化脓扁桃体炎患儿的临床疗效。方法:将98例急性化脓扁桃体炎患儿依据随机数字表法分为对照组和观察组各49例。对照组给予注射用头孢曲松钠静脉滴注治疗,观察组在对照组的基础上加用开喉剑喷雾剂喷喉治疗。2组疗程均为7 d,治疗后比较2组临床疗效及不良反应情况,患者体温复常、扁桃体充血消退、脓性分泌物消失及咽痛消失时间,以及2组治疗前后症状主次症积分、中性粒细胞、C-反应蛋白、白细胞计数水平。结果:观察组临床总有效率为95.92%,对照组为77.55%,2组比较,差异有统计学意义(P<0.05)。观察组体温复常、扁桃体充血消退、脓性分泌物消失及咽痛消失时间均短于对照组(P<0.05)。治疗前,2组的主症、次症积分比较,差异无统计学意义(P>0.05);治疗后,2组的主症、次症积分均较治疗前降低,且观察组主症、次症积分均低于对照组(P<0.05)。治疗前,2组白细胞计数、中性粒细胞以及C-反应蛋白水平比较,差异无统计学意义(P>0.05);治疗后,2组白细胞计数、中性粒细胞、C-反应蛋白水平均较治疗前降低,且观察组上述各项指标均低于对照组(P<0.05)。观察组不良反应发生率为8.16%,对照组为6.12%,2组比较,差异无统计学意义(P>0.05)。结论:开喉剑喷雾剂加注射用头孢曲松钠治疗急性化脓扁桃体炎患儿疗效确切,且安全性良好。Objective:To observe the clinical effect of Kaihoujian sprays combined with cefatriaxone sodiu for injection for acute suppurative tonsillitis in children. Methods:A total of 98 cases of children with acute suppurative tonsillitis were divided into the control group and the observation group according to the random number table method,with 49 cases in each group.The control group was treated with intravenous drip of ceftriaxone sodium for injection, and the observation group was additionally treated with Kaihoujian sprays based on the treatment of the control group. Both groups were treated for seven days. After treatment,clinical effects,incidence of adverse reactions,as well as the time of temperature recovered,tonsil congestion subsided,purulent secretion disappeared and throat pain disappeared were compared between the two groups.The scores of primary and secondary symptoms, neutrophils, C-reactive protein and leukocyte count in the two groups before and after treatment were compared. Results: The total effective rate was 95.92% in the observation group and77.55% in the control group,the difference being significant(P<0.05). The time of temperature recovered,tonsil congestion subsided,purulent secretion disappeared and throat pain disappeared in the observation group was shorter than that in the control group(P<0.05). Before treatment, there was no significant difference being found in the comparison of scores of primary and secondary symptoms between the two groups(P>0.05). After treatment, scores of primary and secondary symptoms in the two groups were decreased when compared with those before treatment, and the two scores in the observation group were lower than those in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of leukocyte counts,neutrophils,and C-reactive protein levels between the two groups(P>0.05). After treatment, leukocyte counts, neutrophils, and C-reactive protein levels in the two groups were decreased when compared with those b

关 键 词：扁桃体炎 儿童 开喉剑喷雾剂 注射用头孢曲松钠 C-反应蛋白 

分 类 号：R766.18[医药卫生—耳鼻咽喉科]