气雾型皮肤冷喷剂对缓解无损伤针穿刺的疼痛效果研究  

Effects of cold spray on pain after non-coring needle insertion into totally implantable access port

作　　者：李佳倩[1] 孙文彦[1] Li Jiaqian;Sun Wenyan(Department of Clinical Nutrition,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医院临床营养科,100730

出　　处：《中华临床营养杂志》2022年第1期45-48,60,共5页Chinese Journal of Clinical Nutrition

基　　金：国家自然科学基金面上项目(71974200)。

摘　　要：目的探讨气雾型皮肤冷喷剂对于缓解无损伤针穿刺疼痛的效果。方法采用随机对照试验设计,将使用无损伤针行输液港维护的患者随机分为试验组与对照组。试验组喷射气雾型皮肤冷喷剂,对照组涂抹复方利多卡因乳膏,比较两组患者的穿刺疼痛度、穿刺成功率、皮肤不良反应、舒适度及满意度。结果试验组与对照组各纳入29例患者。试验组疼痛评分低于对照组[(1.52±1.02)分比(2.24±1.62)分,d=-0.02(95%CI:-0.55~0.51),P=0.109]差异无统计学意义。两组穿刺成功率均为100%,试验组皮肤不良反应发生率较低[绝对危险度=27.6%(95%CI:11.32%~43.86%),P=0.008],舒适度[d=-0.97(95%CI:-0.42~-1.52),P<0.01]及满意度较高[绝对危险度=13.8%(95%CI:1.24%~26.34%),P=0.013],差异有统计学意义。结论气雾型皮肤冷喷剂与复方利多卡因乳膏对无损伤针穿刺的镇痛效果差异无统计学意义,但冷喷剂起效迅速、舒适安全,患者满意度更高。Objective To study the effects of cold spray on pain after non-coring needle insertion.Methods This was a randomized controlled study.Patients with totally implantable access port(TIAP)were randomly divided into the experimental group and the control group.The experimental group were given cold spray,while the control group were given eutectic mixture of local anesthetics cream(EMLA).The severity of pain,comfort and satisfaction,right-first-time insertion rate and skin reaction incidence were compared between groups.Results 29 patients were included in each of the two groups.The pain assessed with numeric rating scale in the experimental group was less severe than the control group([1.52±1.02]vs[2.24±1.62]).However,there was no significant difference(d=-0.02[95%CI:-0.55~0.51],P=0.109).The right-first-time insertion rate was 100%for both groups.The incidence of skin reactions in experimental group was lower(ARR=27.6%[95%CI:11.32%~43.86%],P=0.008),and comfort scores(d=-0.97[95%CI:-0.42~-1.52],P<0.01)and satisfaction scores(ARR=13.8%[95%CI:1.24%~26.34%],P=0.013)were significantly higher compared with control group.Conclusions There was no statistically significant difference in the analgesic effect of cold spray and EMLA on pain from non-coring needle insertion.Cold spray acted quickly,comfortably and safely,resulting in better patient satisfaction.

关 键 词：冷喷剂 复方利多卡因乳膏 完全植入式输液港 无损伤针 疼痛 

分 类 号：R402[医药卫生—临床医学]