基因编辑系统在食用作物中的优化与改造研究进展  

Transformation and Application of Gene Editing Systemin Food Crops

作　　者：朱国宁 张春娇 朱鸿亮[1] ZHU Guoning;ZHANG Chunjiao;ZHU Hongliang(College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083,China;Supervision,Inspection&Testing Center of Agricultural Products Quality,Ministry of Agriculture and Rural Affairs,Beijing 100083)

机构地区：[1]中国农业大学食品科学与营养工程学院,北京100083 [2]农业农村部农产品质量监督检验测试中心(北京),北京100083

出　　处：《未来食品科学》2021年第2期63-73,共11页Future Food Science

基　　金：中央高校基本科研业务费专项基金项目(2020TC032)。

摘　　要：食用作物的育种与人类社会的发展息息相关.随着生物技术的进步,新的育种方法逐渐得到应用.基因编辑系统,尤其是成簇的规律间隔短回文重复序列(clustered regularly interspaced short palindromic repeats,CRISPR)因其廉价、高效、易于操作等特点被广泛应用于食用作物的基因功能研究及育种中.通过改造CRISPR的独特结构获得的表达调控系统与碱基编辑系统,可应用于食用作物的育种过程中.CRISPR技术的进一步优化与成熟必将为食用作物育种带来新的发展与机遇.The breeding of food crops is closely related to the development of human society.With the progress of biotechnology,new breeding methods are gradually applied in practice.Among them,gene editing systems,especially clustered regularly interspaced short palindromic repeats(CRISPR),are widely used in the study of gene function and breeding of food crops because of their low cost,high efficiency and easy operation.Based on CRISPR's unique structure,the CRISPR based expression regu lation system and base editing system were modified and applied to the breeding process of food crops.With the further optimization and maturity of CRISPR technology.it will certainly bring new development and opportunities for crop breeding.

关 键 词：基因编辑 成簇的规律间隔短回文重复序列 碱基编辑系统 食用作物 

分 类 号：S336[农业科学—作物遗传育种]