转座子与转座子相关的非编码小RNA  

Transposable Element and Its Related Non-Coding Small RNA

作　　者：李首道 周明兵[1] LI Shoudao;ZHOU Mingbing(State Key Laboratory of Subtropical Silviculture,College of Forestry and Biotechnology,Zhejiang A&F University,Hangzhou 311300,China)

机构地区：[1]浙江农林大学林业与生物技术学院,亚热带森林培育国家重点实验室,杭州311300

出　　处：《中国细胞生物学学报》2022年第2期362-371,共10页Chinese Journal of Cell Biology

基　　金：浙江自然科学基金重点项目(批准号:LZ19C160001);国家自然科学基金(批准号:31870656、31470615)资助的课题。

摘　　要：转座子是一种在真核生物基因组中大量存在的可移动DNA序列。非编码小RNA具有广泛的生物学功能,能够在不同层面影响基因的表达。在许多真核生物基因组中,转座子是非编码小RNA的重要来源。最近的一些研究发现,转座子和其衍生非编码小RNA在基因调控中发挥着重要作用,但是国内相关的综述却较少。所以该文从转座子与其衍生的非编码小RNA的关系,这些小RNA在基因组和生物进化中扮演的角色两方面,对现阶段关于转座子和非编码小RNA的相关研究成果进行综述。TEs (transposable elements) are a large number of mobile DNA sequences in eukaryotic genome.The non-coding small RNA has a wide range of biological functions and can affect gene expression at different levels.In many eukaryotic genomes,transposons are important sources of non-coding small RNAs.Recent studies have also found that transposons and their derived non-coding small RNAs play an important role in gene regulation.In this paper,the roles of transposons and their derived non-coding small RNAs in plant and animal genomes are discussed from the following aspects:the relationship between transposons and their derived non coding regulatory small RNAs,the roles of transposons and non-coding regulatory small RNAs in genome and biological evolution.The current research achievements of transposons and non-coding small RNAs are reviewed.

关 键 词：转座子 非编码小RNA 微小RNA 

分 类 号：Q522[生物学—生物化学]