运动康复对维持性血液透析患者营养状态及疲乏综合征的影响  

Effect of exercise rehabilitation on nutritional status and fatigue syndrome in maintenance hemodialysis patients

作　　者：蔡国梅[1] 胡静雯 王全蕊[3] 高运 冯超 武文斌[1] 常玲玲[1] 柴春香[6] CAI Guomei;HU Jingwen;WANG Quanrui;GAO Yun;FENG Chao;WU Wenbin;CHANG Lingling;CHAI Chunxiang(Department of Nephrology,Weifang Yidu Central Hospital,Shandong Province,Weifang 261000,China;Department of Nephrology,Liaocheng People′s Hospital,Shandong Province,Liaocheng 252000,China;Department of Pediatric,Weifang Yidu Central Hospital,Shandong Province,Weifang 261000,China;Department of Nephrology,Weifang Endocrine and Metabolic Disease Hospital,Shandong Province,Weifang 261000,China;Department of Nephrology,Shouguang Hexin Hospital,Shandong Province,Weifang 261000,China;Department of Immunology and Rheumatology,Affiliated Hospital of Weifang Medical College,Shandong Province,Kuiwen 261000,China)

机构地区：[1]山东省潍坊市益都中心医院肾内科,山东潍坊261000 [2]山东省聊城市人民医院肾内科,山东聊城252000 [3]山东省潍坊市益都中心医院儿内科,山东潍坊261000 [4]山东省潍坊内分泌与代谢病医院肾内科,山东潍坊261000 [5]山东省寿光和信医院肾内科,山东潍坊261000 [6]潍坊医学院附属医院免疫风湿科,山东奎文261000

出　　处：《中国当代医药》2022年第16期140-143,147,共5页China Modern Medicine

基　　金：山东省潍坊市卫生健康委科研项目计划(WFWSJK-2020-040)。

摘　　要：目的探讨运动康复对维持性血液透析(MHD)患者营养状态及疲乏综合征的影响。方法选取2019年6月至2020年10月潍坊医学院附属医院及益都中心医院收治的88例维持性血液透析患者作为研究对象,按照随机数字表法分为运动组(n=44)和对照组(n=44)。对照组给予常规干预,运动组在血液透析过程中进行运动康复。比较两组患者治疗前后的临床指标[尿素清除指数(Kt/V)、血红蛋白(Hb)、碳酸氢根(HCO_(3)^(-))、血清白蛋白(Alb)]和体质相关因素[肱三头肌皮褶厚度(TSF)、上臂中部周径(MAC)、上臂中部肌围(MAMC)、握力(HGS)、体重指数(BMI)、肌肉组织质量(LTM)、疲劳评定量表(FAI)评分]。结果两组患者干预前后的Kt/v,HCO_(3)^(-)比较,差异无统计学意义(P>0.05)。干预后,运动组的Hb,Alb高于对照组,差异有统计学意义(P<0.05)。两组患者干预前后的TSF比较,差异无统计学意义(P>0.05)。干预后,运动组的MAC、MAMC、HGS,BMI、LTM高于对照组,FAI低于对照组,差异有统计学意义(P<0.05)。结论运动康复能改善患者营养状态,减轻患者疲乏综合征症状,值得临床推广。Objective To investigate the effects of exercise rehabilitation on nutritional status and fatigue syndrome in patients with maintenance hemodialysis(MHD).Methods A total of 88 patients with maintenance hemodialysis admitted to Affiliated Hospital of Weifang Medical College and Weifang Yidu Central Hospital from June 2019 to October 2020 were selected as the research objects,and were divided into exercise group(n=44)and control group(n=44)according to random number table method.The control group received routine intervention,and the exercise group received exercise rehabilitation during hemodialysis.The clinical indicators(Kt/vurea[Kt/V],hemoglobin[Hb],bicarbonate[HCO_(3)^(-)],serum albumin[Alb])and constitution-related factors(triceps skinfold thickness[TSF],mid-upper arm circumference[MAC],mid-arm muscle circumference[MAMC],hand gripping strength[HGS],body mass index[BMI],lean tissue mass[LTM],fatigue assessment instrument[FAI]score)of the two groups were compared before and after treatment.Results There were no significant differences in Kt/V and HCO_(3)^(-) between the two groups before and after intervention(P>0.05).After in tervention,Hb and Alb in the exercise group were higher than those in the control group,with statistical significances(P<0.05).There was no significant difference in TSF between two groups before and after intervention(P>0.05).After intervention,MAC,MAMC,HGS,BMI and LTM in the exercise group were higher than those in the control group,while FAI was lower than that in the control group,with statistical significances(P<0.05).Conclusion Exercise rehabilitation can improve the nutritional status of patients and alleviate the symptoms of fatigue syndrome.

关 键 词：血液透析 运动康复 营养状态 疲乏综合征 

分 类 号：R459.5[医药卫生—治疗学]