纳米载药系统的研究进展  

Research Progress of Nanometer Drug Delivery System

作　　者：卓新雨 张艾立 马菲 崔志磊[3] 刘臻 谢恬[2] Zhuo Xinyu;Zhang Aili;Ma Fei;Cui Zhilei;Liu Zhen;Xie Tian(School of Basic Medical Science,Hangzhou Normal University,Hangzhou 311121;College of Pharmacy,School of Medicine,Hangzhou Normal University,Hangzhou 311121;Department of Respiratory Medicine,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]杭州师范大学基础医学院,浙江杭州311121 [2]杭州师范大学药学院,浙江杭州311121 [3]上海交通大学医学院附属新华医院呼吸科,上海200092

出　　处：《广东化工》2022年第10期85-87,共3页Guangdong Chemical Industry

基　　金：2021~2022年杭州师范大学“本科生创新能力提升工程”。

摘　　要：纳米载药系统是指由无机或高分子材料形成的纳米级微观范畴的亚微粒药物载体输送系统。纳米载药系统具有改善药物性能、增强药物靶向性、提高生物利用度、降低药物毒副作用等优势,正成为新型给药系统的研究热点,至今已经开发了纳米颗粒、纳米脂质体、纳米胶束及纳米乳液等。本文对纳米载药系统近10年来的发展状况做如下整理和分析,以供后续研究者和临床工作者参考。Drug-loading nanoparticles drug delivery system refers to the drugs and materials together to form the nano-scale microscopic category of particulate drug carrier conveying system,as a new research hot spot in drug delivery system,improve the drug absorption,drug targeting,improve bioavailability,reduce the side effects of drugs,the improvement of drug circulation and the advantages of the distribution in the body,nano-particles,nano-liposomes,nano-micelles,nano-emulsions and suspensions have been developed.In this paper,the development of nano-drug delivery system in the past 10 years is summarized and analyzed as follows for the reference of subsequent researchers and clinical workers.

关 键 词：纳米材料 载药系统 靶向性 低毒性 制备方法 

分 类 号：TQ[化学工程]