低相对分子质量肝素治疗腹腔镜阑尾切除术围术期阑尾炎合并心血管病患者的疗效观察  

Clinical Observation of Low Molecular Weight Heparin in the Treatment of Peri Operative Appendicitis Complicated with Cardiovascular Disease after Laparoscopic Appendectomy

作　　者：毕林刚 BI Lin-gang(Department of General surgery,The Central Hospital of Yingkou,Yingkou,115003,China)

机构地区：[1]营口市中心医院普外科,营口115003

出　　处：《血栓与止血学》2022年第3期379-380,共2页Chinese Journal of Thrombosis and Hemostasis

摘　　要：目的探讨低相对分子质量肝素(LMWH)在腹腔镜阑尾切除术围术期阑尾炎合并心血管病患者中的应用价值。方法以156例接受腹腔镜阑尾切除术患者为对象,随机分为观察组(围术期应用LMWH)与对照组(常规治疗)。对比两组手术指标及心功能指标。结果两组出血量及手术时间比较无差异(P>0.05)。观察组下肢深静脉血栓形成(DVT)发生率为1.28%(1/78),低于对照组10.26%(8/78)(P<0.05)。两组心肌肌钙蛋白I(cTnI)、B型钠尿肽(BNP)水平比较无差异(P>0.05)。结论阑尾炎合并心血管疾病患者围术期应用LMWH未增加术中出血,对心肌功能无明显损伤,但可减少DVT的发生。Objective To investigate the application value of low molecular weight heparin(LMWH)in patients with appendicitis and cardiovascular disease during laparoscopic appendectomy.Methods 156 cases of laparoscopic appendectomy patients were randomly divided into observation group(perioperative application of low molecular weight heparin)and control group(conventional treatment).The operation indexes and cardiac function indexes of the two groups were compared.Results There was no difference in blood loss and operation time between the two groups(P>0.05).The incidence of LDVT in the observation group was1.28%(1/78),which was lower than that in the control group 10.26%(8/78)(P<0.05).There was no difference in the levels of cardiac troponin I(cTnI)and B-type natriuretic peptide(BNP)between the two groups(P>0.05).Conclusion The perioperative application of low molecular weight heparin in patients with appendicitis and cardiovascular disease does not increase intraoperative blood loss,has no obvious damage to myocardial function,and can reduce the incidence of DVT.

关 键 词：低相对分子质量肝素 腹腔镜阑尾切除术 阑尾炎 心血管病 

分 类 号：R656.8[医药卫生—外科学]