^(90)Y树脂微球选择性内放射治疗放射防护检测与剂量评估  

Radiological protection detection and dose assessment of selective internal radiotherapy with ^(90)Y resin microspheres

作　　者：练德幸[1] 寇珊珊 陆见霏 张庆召[1] 朱卫国[1] 王川健[2] 侯长松[1] Lian Dexing;Kou Shanshan;Lu Jianfei;Zhang Qingzhao;Zhu Weiguo;Wang Chuanjian;Hou Changsong(Key Laboratory of Radiological Protection and Nuclear Emergency,China CDC,National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing 100088,China;Hainan Center for Disease Control and Prevention,Haikou 570203,China)

机构地区：[1]中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室,北京100088 [2]海南省疾病预防控制中心,海口570203

出　　处：《中华放射医学与防护杂志》2022年第5期385-390,共6页Chinese Journal of Radiological Medicine and Protection

摘　　要：目的对90Y树脂微球选择性内放射治疗过程进行放射防护检测和剂量评估,为放射防护工作提供参考。方法对90Y树脂微球介入手术治疗各操作环节和患者体表的外照射水平进行检测,估算相关人员的受照剂量水平。结果90Y树脂微球分装及转运过程的剂量率水平为1.12~454μSv/h,手术操作过程为2.06~58.2μSv/h;3名患者术后0.5 h,体表5 cm和1 m处的剂量率分别为22.7~64.1和0.82~2.55μSv/h。按照每年200例患者的工作量,90Y树脂微球药物操作对工作人员年个人有效剂量贡献为0.12~1.03 mSv/年,术后患者对公众、家属及陪护志愿者的个人有效剂量贡献为0.02~0.24 mSv/年。结论在患者治疗、护理和出院过程中,工作人员、陪护志愿者和公众的照射剂量均低于(GB 18871-2002«电离辐射防护与辐射源安全基本标准»)中的剂量限值和医疗机构设定的管理目标值。Objective To conduct radiation detection and dose assessment in selective internal radiotherapy with 90Y resin microspheres for the purpose of providing a reference for radiological protection.Methods The dose rates from radiotherapy with 90Y resin microspheres were detected in the process of each operation at different distances from the body surface of patients the levels of dose to the persons concerned were compared with the relevant national regulations and standards.Results The estimated dose rates were 1.12-454μSv/h during 90Y resin microspheres dispensing and 2.06-58.2μSv/h during surgical procedure.The dose rates at 0.5 h after surgery were 22.7-64.1μSv/h at 5 cm and 0.82-2.55μSv/h at 1 m from three patient′s body surface.Assuming treating 200 patients a year,the annual individual effective dose to the radiation workers was 0.12-1.03 mSv/year.The annual individual effective dose to the public,comforters and carers of patients was 0.02-0.24 mSv/year after release of a patient.Conclusions During the treatment,nursing and release of patients,the radiation doses to workers,carers and the public are lower than the individual dose limit given in the GB18871-2002 basic standards for protection against ionizing radiation and for the safety of radiation sources and the management target value set by of the relevant medical institutions.

关 键 词：^(90)Y 树脂微球 内放射治疗 放射防护 

分 类 号：R144[医药卫生—公共卫生与预防医学]