针刺五脏背俞穴联合推拿背部足太阳膀胱经治疗肝郁脾虚型慢性疲劳综合征的临床疗效及对患者T淋巴细胞亚群和血脂指标的影响  

Curative effect of the combined therapy of acupuncture at back-shu-point of five organs and massage for chronic fatigue syndrome of liver stagnation spleen deficiency and the regulatory effect on immunity and dyslipidemia

作　　者：孙冬玮 武明霞 倪晓诚 薛利圆 张春红 SUN Dongwei;WU Mingxia;NI Xiaocheng;XUE Liyuan;ZHANG Chunhong(Department of Acupuncture,Shenzhen Bao'an Authentic TCM Therapy Hospital,Shenzhen,Guangdong 518000)

机构地区：[1]广东省深圳市宝安纯中医治疗医院针灸科,广东深圳518000

出　　处：《河北中医》2022年第2期275-279,共5页Hebei Journal of Traditional Chinese Medicine

基　　金：深圳市卫生和计划生育委员会系统科研项目(编号:201606058)。

摘　　要：目的观察针刺五脏背俞穴联合推拿背部足太阳膀胱经治疗肝郁脾虚型慢性疲劳综合征(CFS)的临床疗效及对患者T淋巴细胞亚群和血脂的影响。方法将84例肝郁脾虚型CFS患者按照随机数字表法分为2组,对照组42例(实际完成研究39例)采用针刺五脏背俞穴治疗,治疗组42例(实际完成研究41例)采用针刺五脏背俞穴联合推拿背部足太阳膀胱经治疗。2组均治疗4周后统计疗效,比较2组治疗前后中医证候(包括神疲乏力、情绪抑郁或急躁易怒、善太息、周身不适、夜寐欠安、胃脘疼痛或胁肋胀痛、腹胀、食少纳呆、肠鸣矢气)积分、疲劳量表-14(FS-14)评分(包括体力疲劳、脑力疲劳)、T淋巴细胞亚群(包括CD3^(+)、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))、血脂指标[包括总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]变化情况。结果治疗组总有效率92.68%(38/41),对照组总有效率74.36%(29/39),治疗组疗效优于对照组(P<0.05)。2组治疗后中医证候神疲乏力、情绪抑郁或急躁易怒、善太息、周身不适、夜寐欠安、胃脘疼痛或胁肋胀痛、腹胀、食少纳呆、肠鸣矢气评分和总分与本组治疗前比较均降低(P<0.05),且治疗组治疗后神疲乏力、情绪抑郁或急躁易怒、胃脘疼痛或胁肋胀痛、食少纳呆评分和总分均低于对照组(P<0.05)。2组治疗后FS-14体力疲劳、脑力疲劳评分和总分与本组治疗前比较均降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。与本组治疗前比较,2组治疗后T淋巴细胞亚群CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均升高(P<0.05),CD8^(+)水平均降低(P<0.05),且治疗组治疗后各指标改善均优于对照组(P<0.05)。与本组治疗前比较,2组治疗后血脂指标TC、TG、LDL-C水平均降低(P<0.05),HDL-C水平均升高(P<0.05),且治疗组治疗后各指标改善均优于对照组(P<0.05)。结论针刺五脏背俞穴联合�Objective To observe the clinical efficacy of the combined therapy of acupuncture at back-shu-point of five organs and massage of the bladder meridian of foot-taiyang on the back for chronic fatigue syndrome(CFS)of liver stagnation spleen deficiency and the regulatory effect on immunity and dyslipidemia.Methods Totally 84 CFS patients(liver stagnation spleen deficiency)were randomly assigned into the treatment group(n=42,1 shedding)and the control group(n=42,3 shedding);apart from the acupuncture at back-shu-point of five organs,and patients in the treatment group were additionally treated with massage of the bladder meridian of foot-taiyang on the back.Treated for 4 weeks,the aiming was to compare traditional Chinese medicine(TCM)syndrome(tiredness,depression or irritability,like to sigh,discomfort,insomnia,epigastric pain or hypochondrium distending pain,abdominal distension,anorexia,bowel sounds)scores,Fatigue Scale-14(FS-14)(physical fatigue,mental fatigue)scores,immune function(T lymphocyte CD3^(+),CD4^(+),CD8^(+),CD4^(+)/CD8^(+)),blood lipid indexes(total cholesterol[TC],triglyceride[TG],high density lipoprotein-cholesterol[HDL-C],low-density lipoprotein cholesterol[LDL-C]);the curative effect was assessed.Results After treatment,The overall effective rate was obviously superior for the treatment group compared with the control group(92.68%[38/41]vs 74.36%[29/39],[P<0.05],respectively);TCM symptom scores in the two groups were decreased(P<0.05),TCM symptom scores including tiredness,depression or irritability,epigastric pain or hypochondrium distending pain,anorexia were significantly decreased in the treatment group relative to the control group(P<0.05);FS-14 scores in groups down-regulated(P<0.05),FS-14 scores down-regulated markedly in the treatment group relevant to the control group(P<0.05);The level of CD3^(+),CD4^(+),CD4^(+)/CD8^(+)in groups decreased(P<0.05),whereas the level of CD8^(+)increased(P<0.05),the effect of the treatment group was significantly superior to that of the control group in thos

关 键 词：疲劳综合征 慢性 肝郁脾虚 针刺疗法 推拿 穴 背俞 足太阳膀胱经 免疫调节 血脂异常 

分 类 号：R246.1[医药卫生—针灸推拿学] R597.9[医药卫生—中医临床基础]