酚类抗氧剂BHT的应用和降解路径的研究进展  

Research progress on application and degradation pathway of phenolic antioxidant BHT

作　　者：周军伟 陈建发 万代红 张惠坤 汪蓉 ZHOU Jun-wei;CHEN Jian-fa;WAN Dai-hong;ZHANG Hui-kun;WANG Rong(School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210023,China;Shanghai Space Propulsion Technology Research Institute,Shanghai 201100,China)

机构地区：[1]南京大学化学化工学院,江苏南京210023 [2]上海航天动力技术研究所,上海201100

出　　处：《应用化工》2022年第4期1077-1082,共6页Applied Chemical Industry

基　　金：国家自然科学基金资助(21973041,21734005);国防科技基础加强计划资助(2019JCJQZD178)。

摘　　要：综述了2,6-二叔丁基对甲酚(Butylated hydroxytoluene,BHT)在不同领域的应用,总结了BHT及其分解产物对环境和生物的潜在毒性。结果表明,抗氧剂BHT在生物医药、能源、食品与材料化学等领域有着广泛的应用,以BHT为基体设计新型抗氧化剂可以有效拓展其应用范围。BHT大部分降解产物向着毒性降低的方向进行,但是降解产物BHT-Q、BHT-tert-BuOH等毒性高于BHT。研究BHT及其降解产物的毒性机理可以揭示其在不同物种中的代谢差异和作用机制,可为BHT的应用以及改性提供理论依据。Discussed the application of BHT in various fields,and summarizes the potential toxicity of BHT and its decomposition products to the environment and organisms.The results show that the antioxidant BHT has a wide range of applications in the fields of biomedicine,energy,food and material chemistry,and the design of a new antioxidant based on BHT can effectively expand its application range.Most of the degradation products of BHT proceed towards the direction of reduced toxicity,but the degradation products BHT-Q and BHT-tert-BuOH are more toxic than BHT.Studying the toxicity mechanism of BHT and its degradation products can reveal its metabolic differences and mechanism of action in different species,and can provide a theoretical basis for the application and modification of BHT.

关 键 词：BHT 应用进展 稳定性 降解 危害 

分 类 号：TQ314.24[化学工程—高聚物工业]