CT数据建立12岁儿童全颈椎有限元模型及有效性验证  

Finite element model of the 12-year-old child whole cervical spine:establishment and validity verification based on CT data

作　　者：刘清华 蔡永强[2] 金凤 于静红 王海燕 张云凤 王利东 李佳伟 王星 和雨洁 戴丽娜 王建忠[5] 邬超 仝铃 康志杰 李志军[2,5] 李筱贺 Liu Qinghua;Cai Yongqiang;Jin Feng;Yu Jinghong;Wang Haiyan;Zhang Yunfeng;Wang Lidong;Li Jiawei;Wang Xing;He Yujie;Dai Lina;Wang Jianzhong;Wu Chao;Tong Ling;Kang Zhijie;Li Zhijun;Li Xiaohe(Graduate Schoo,,Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia Autonomous Region,China;Digital Medicine Center(Digital Translational Medicine Engineering Technology Research Center of Inner Mongolia Autonomous Region),Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia Autonomous Region,China;Department of Human Anatomy,Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia Autonomous Region,China;Department of Imaging,Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia Autonomous Region,China;Department of Imaging,the Second Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia Autonomous Region,China;Department of Imaging,Inner Mongolia International Mongolian Hospital,Hohhot 010000,Inner Mongolia Autonomous Region,China)

机构地区：[1]内蒙古医科大学研究生院,内蒙古自治区呼和浩特市010000 [2]内蒙古医科大学数字医学中心(内蒙古自治区数字转化医学工程技术研究中心),内蒙古自治区呼和浩特市010000 [3]内蒙古医科大学人体解剖教研室,内蒙古自治区呼和浩特市010000 [4]内蒙古医科大学附属医院影像科,内蒙古自治区呼和浩特市010000 [5]内蒙古医科大学第二附属医院影像科,内蒙古自治区呼和浩特市010000 [6]内蒙古自治区国际蒙医医院影像科,内蒙古自治区呼和浩特市010000

出　　处：《中国组织工程研究》2023年第4期500-504,共5页Chinese Journal of Tissue Engineering Research

基　　金：内蒙古自然科学基金(2020MS08124),项目负责人:李筱贺;内蒙古自治区“草原英才”工程青年创新创业人才项目(2020),项目负责人:李筱贺;内蒙古医科大学科技百万项目(YKD2017KJBW012),项目负责人:王海燕;内蒙古医科大学后续科研项目(2020),项目负责人:李筱贺;内蒙古科技计划项目(2019GG115),项目负责人:李志军。

摘　　要：背景:儿童颈椎有限元模型多为10岁及以下儿童的,所建立的节段也只是部分颈椎,而12岁儿童全颈椎有限元模型则相对较少。目的:建立有效的12岁儿童全颈椎有限元模型,为研究儿童颈椎活动性、应力及临床治疗儿童颈椎疾病提供理论依据。方法:随机选择1名健康的12岁儿童,使用64排螺旋CT对该儿童颈椎进行扫描,将CT数据导入Mimics 16.0中重建简单的三维模型,用Cero 5.0优化模型,再导入Hypermesh 14.0中划分网格及添加韧带,最后用ANSYS 6.14软件进行材料赋值,设定边界等操作,构建颈椎三维有限元模型,并对模型有效性进行验证,将模型在前屈后伸、左右屈曲、左右旋转6种工况下各椎体的活动度与文献数据进行对比。结果与结论:通过有限元软件成功建立了12岁儿童全颈椎三维有限元模型,该模型还原度高,与其模拟的颈椎相似性好。在1.5 N•m的载荷下,除C4-5、C6-7在旋转工况下的活动度较参考文献低外,其余节段在各种工况下的活动度均在既往文献的参考范围内,说明该模型有效,在后续的应力研究和临床治疗中可以运用。BACKGROUND:The finite element model of the pediatric cervical spine is mostly established in children aged 10 years old or younger,and the established segments are only a part of the cervical spine,while the finite element model of the 12-year-old child whole cervical spine is rarely reported.OBJECTIVE:To establish a finite element model of the 12-year-old child whole cervical spine,providing a theoretical basis for studying cervical spine mobility and stress and clinical treatments for cervical spine diseases in children.METHODS:A healthy child aged 12 years old was selected randomly,and a 64-row spiral CT was used to obtain the image of the child’s cervical spine.Then the CT data were introduced into the Mimics 16.0 to reconstruct a three-dimensional model.CERO 5.0 software was used to input the model into Hypermesh 14.0,which could divide the mesh and add ligaments.Subsequently,ANSYS 6.14 software was used to perform material assignment and set boundaries to construct a three-dimensional finite element model of the cervical spine.The validity of the model was finally verified.The range of motion of each vertebral body was compared with literature data under six working conditions of the model:flexion and extension,left and right flexion and extension,and left and right rotation.RESULTS AND CONCLUSION:The three-dimensional finite element model of the 12-year-old child whole cervical spine was successfully established using the finite element software.The model had a high degree of reduction and nice similarity to the child’s cervical spine.Under the load of 1.5 N▪m,the mobility of the C4-5 and C6-7 in rotating conditions was lower than previously reported,and the mobility of the remaining segments in various conditions was within the reference range as previously reported.Thus,this model is available for subsequent stress research and clinical treatment.

关 键 词：全颈椎 有限元分析 儿童 有效性验证 活动度 

分 类 号：R459.9[医药卫生—治疗学] R496[医药卫生—临床医学] R318