不同运动模式对超重和肥胖者Chemerin影响的研究进展  

Research Progress of the Effects of Different Exercise Modes on Chemerin in the Serum of Overweight and Obesity

作　　者：万泽睿 郑彭[1] 赵一瑾[1] WAN Zerui;ZHENG Peng;ZHAO Yijin(School of Rehabilitation Medicine,Southern Medical University,Shunde Guangdong 528305,China;Henan Vocational College of Nursing,Anyang He’nan 455000,China)

机构地区：[1]南方医科大学康复医学院,广东顺德528305 [2]河南护理职业学院,河南安阳455000

出　　处：《中国继续医学教育》2022年第11期194-198,共5页China Continuing Medical Education

基　　金：2019年广东省高等教育教学改革项目(140);2020年南方医科大学校级大学生创新创业训练计划项目(X202012121353)。

摘　　要：Chemerin是孤独G蛋白偶联受体Chemerin R的内源性配体,于2007年被鉴定为脂肪因子,在炎症、糖脂代谢、血管生成方面发挥重要作用。众所周知,运动是防治肥胖的有效手段,近年来大量研究显示超重与肥胖患者血清Chemerin水平明显增加,并且增加程度与肥胖程度相关,Chemerin可能成为衡量肥胖严重程度的标准之一,而运动可以降低超重与肥胖者血清Chemerin水平,因此猜测Chemerin是否能够作为衡量超重与肥胖患者的运动效果标准之一,以及通过测量Chemerin能否防治早期的肥胖产生,但尚未有研究证明哪种运动模式更为有效。有氧运动安全但耗时,高强度间歇性运动省时但可能有一定的运动风险,这为下一步研究提供了方向。Chemerin is a natural ligand for an orphan G protein-coupled receptors(GPCRs)-Chemerin receptors,which was identified as an adipokine in 2007.Chemerin plays an important role in inflammatory,glycolipid metabolism,and angiogenesis.As we all known,Exercise is an effective way to prevent and control obesity.In recent years,a number of studies have shown that the levels of Chemerin in the serums were significantly increased in the over wight and obesity,and the degree of increase is related to the degree of obesity,therefore C h e m e r i n may become one of the standards for measuring the severity of obesity.Exercise decreases Chemerin in the serum of overweight and obesity,so it is speculated whether chemerin can be used as one of the standards for measuring the exercise effect of the overweight and obesity,and whether people can prevent early obesity by measuring chemerin.Aerobics and High-intensity Intermittent-training decreases Chemerin in the serum of overweight and obesity,but there is no research to prove which exercise mode is more effective,which provides direction for the next step of research.

关 键 词：脂肪因子 CHEMERIN 超重 运动 肥胖 有氧运动 HIIT 

分 类 号：R34[医药卫生—基础医学]