神经内镜微创手术对高血压脑出血患者并发症及生活质量的影响  

Effect of Neuroendoscopic Minimally Invasive Surgery on Complications and Quality of Life in Patients with Hypertensive Intracerebral Hemorrhage

作　　者：陈文远[1] 陈金龙[1] 邵合队[1] 蒋财谋[1] 郭之通[1] CHEN Wenyuan;CHEN Jinlong;SHAO Hedui;JIANG Caimou;GUO Zhitong(Department of Neurosurgery,Xiamen Third Hospital,Xiamen,Fujian Province,361100 China)

机构地区：[1]福建省厦门市第三医院神经外科,福建厦门361100

出　　处：《中外医疗》2022年第13期65-69,共5页China & Foreign Medical Treatment

摘　　要：目的 探讨神经内镜微创手术对高血压脑出血患者的治疗效果,及对并发症及生活质量的影响。方法方便选取2016年3月—2021年3月期间该院收治的130例高血压脑出血患者,以随机分组原则分组,观察组(n=65)以神经内镜微创手术治疗,对照组(n=65)以传统开颅手术治疗,比较两组效果。结果 观察组总有效率高于对照组(90.77%vs 69.23%),差异有统计学意义(χ^(2)=9.423,P=0.002)。观察组手术时间、术后住ICU时间、术中出血量均优于对照组,差异有统计学意义(P<0.05);术后3个月,观察组格拉斯哥预后评分(GOS)明显高于对照组,差异有统计学意义(P<0.05)。术前,两组患者认知功能(MMSE)、日常生活能力(ADL)评分对比,差异无统计学意义(P>0.05),术后3个月观察组各指标评分均高于对照组,差异有统计学意义(P<0.05)。术后观察组患者血浆内皮素(ET)、C-反应蛋白(CRP)、白介素(IL-6)水平水平均低于对照组,差异有统计学意义(P<0.05)。观察组患者并发症发生率低于对照组(6.15%vs 20.00%),差异有统计学意义(χ^(2)=5.481,P=0.019)。结论神经内镜微创手术在高血压脑出血患者中的应用价值显著,有利于提升患者日常生活能力,减少并发症发生,可推广。Objective To investigate the therapeutic effect of neuroendoscopic minimally invasive surgery on patients with hypertensive intracerebral hemorrhage,and its impact on complications and quality of life.Methods A total of 130 patients with hypertensive intracerebral hemorrhage admitted to the hospital from March 2016 to March 2021 were conveniently selected and randomly divided into groups.The observation group(n=65)was treated with neuroendoscopic minimally invasive surgery,and the control group(n=65)was treated with traditional craniotomy.The effects of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group(90.77%vs 69.23%),the difference was statistically significant(χ^(2)=9.423,P=0.002).The operation time,postoperative ICU stay time,and intraoperative blood loss in the observation group were better than those in the control group,the difference was statistically significant(P<0.05);three months after the operation,the Glasgow Outcome Scale(GOS)of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Before operation,there was no statistically significant difference in the scores of cognitive function(MMSE)and activities of daily living(ADL)between the two groups,the difference was not statistically significant(P>0.05),and the scores of each index in the observation group were higher than those in the control group 3 months after operation,the difference was statistically significant(P<0.05).After operation,the levels of plasma endothelin (ET), C-reactive protein (CRP) and interleukin (IL-6) in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05). The incidence of complications in the observation group was lower than that in the control group (6.15% vs 20.00%),the difference was statistically significant(χ^(2)=5.481, P=0.019). Conclusion The application value of neuroendoscopic minimally invasive s

关 键 词：神经内镜微创手术 高血压脑出血 并发症 

分 类 号：R4[医药卫生—临床医学]