舒芬太尼与丙泊酚联合麻醉对于腹腔镜下子宫肌瘤切除术患者血流动力学的影响  

Effects of Sufentanil and Propofol Combined Anesthesia on Hemodynamics in Patients Undergoing Laparoscopic Myomectomy

作　　者：朱向晖[1] 王帅 张红 ZHU Xianghui;WANG Shuai;ZHANG Hong(Department of Anesthesiology,Heze Municipal Hospital,Heze,Shandong Province,274000 China;Department of Operating Room,Heze Municipal Hospital,Heze,Shandong Province,274000 China)

机构地区：[1]菏泽市立医院麻醉科,山东菏泽274000 [2]菏泽市立医院手术室,山东菏泽274000

出　　处：《中外医疗》2022年第13期82-85,共4页China & Foreign Medical Treatment

摘　　要：目的 探讨腹腔镜下子宫肌瘤切除术患者在舒芬太尼与丙泊酚麻醉下开展手术对于血流动力学的影响。方法 2020年6月—2021年5月方便选择该院96例行腹腔镜下子宫肌瘤切除术患者为研究对象,按照随机数表划分组别,每组48例。对照组使用芬太尼与丙泊酚复合麻醉,研究组使用舒芬太尼与丙泊酚复合麻醉。比较两组不同时间点[麻醉前(T0)、气管插管即刻(T1)、开始手术时(T2)、建立气腹10 min(T3)与完成手术时(T4)]的血流动力学指标变化,以及麻醉相关不良反应情况。结果 研究组T1、T2、T3、T4时间点的心率为(79.20±7.20)、(78.51±8.46)、(79.20±12.03)、(79.55±7.47)次/min显著低于对照组(83.80±7.30)、(84.92±8.79)、(88.76±8.65)、(84.40±6.45)次/min,差异有统计学意义(t=3.108、3.640、4.470、3.405,P<0.001);研究组的平均动脉压为(12.20±1.20)、(11.95±1.52)、(12.13±1.30)、(11.42±1.03)k Pa显著低于对照组(13.20±1.85)、(12.95±1.22)、(13.50±1.46)、(12.62±1.50)k Pa,差异有统计学意义(t=3.142、3.555、4.855、4.569,P<0.001)。两组麻醉不良反应发生率对比差异无统计学意义(P>0.05)。结论 腹腔镜下子宫肌瘤切除术患者使用舒芬太尼与丙泊酚协同麻醉能够维持血流动力学的稳定性。Objective To investigate the effect of laparoscopic myomectomy under sufentanil and propofol anesthesia on hemodynamics.Methods From June 2020 to May 2021,96 patients in the hospital who underwent laparoscopic myomectomy were conveniently selected as the research subjects,and were divided into groups according to the random number table,with 48 cases in each group.The control group was anesthetized with fentanyl and propofol,and the study group was anesthetized with sufentanil and propofol.The hemodynamic indexes were compared between the two groups at different time points[before anesthesia(T0),immediately after endotracheal intubation(T1),at the beginning of the operation(T2),10 minutes after the establishment of pneumoperitoneum(T3),and at the completion of the operation(T4)].changes,and anesthesia-related adverse reactions.Results The heart rate at time points T1,T2,T3,and T4 in the study group was significantly lower at(79.20±7.20)times/min,(78.51±8.46)times/min,(79.20±12.03)times/min,and(79.55±7.47)times/min,in the control group(83.80±7.30)times/min,(84.92±8.79)times/min,(88.76±8.65)times/min,(84.40±6.45)times/min,the difference was statistically significant(t=3.108,3.640,4.470,3.405,P<0.001);the mean arterial pressure of the study group(12.20±1.20)kPa,(11.95±1.52)kPa,(12.13±1.30)kPa,(11.42±1.03)kPa was significantly lower than that of the control group(13.20±1.85)kPa,(12.95±1.22)kPa,(13.50±1.46)kPa,(12.62±1.50)kPa,the difference was statistically significant(t=3.142,3.555,4.855,4.569,P<0.001).There was no statistically significant difference in the incidence of adverse reactions of anesthesia between the two groups (P>0.05). Conclusion Co-anesthesia with sufentanil and propofol can maintain hemodynamic stability in patients undergoing laparoscopic myomectomy.

关 键 词：舒芬太尼 丙泊酚 麻醉 腹腔镜下 宫肌瘤切除术 血流动力学 

分 类 号：R4[医药卫生—临床医学]