布托啡诺与地佐辛超前镇痛在小儿腹腔镜疝气手术术后镇痛中的临床探讨  

Clinical Study of Butorphanol and Dezocine Preemptive Analgesia in Postoperative Analgesia in Children with Laparoscopic Hernia Surgery

作　　者：谢铁骊[1] XIE Tieli(Department of Anesthesiology,Peixian People's Hospital,Peixian,Jiangsu Province,221600 China)

机构地区：[1]沛县人民医院麻醉科,江苏沛县221600

出　　处：《中外医疗》2022年第13期102-105,共4页China & Foreign Medical Treatment

摘　　要：目的 探讨布托啡诺与地佐辛超前镇痛在小儿腹腔镜疝气手术术后镇痛中的效果。方法 方便选取2020年7月—2021年7月在该院进行腹腔镜疝气手术的患儿90例,按照随机抽签法进行分组,其中30例为安慰组,30例为对照组,30例为研究组。对照组超前镇痛中应用布托啡诺,研究组超前镇痛中应用地佐辛,安慰组超前镇痛中应用生理盐水,对3组苏醒期躁动发生情况、镇痛效果、镇静效果、不良反应发生情况进行观察与记录,之后对观察结果进行比较。结果 对照组与研究组苏醒期躁动发生率均为6.67%,明显低于安慰组,差异有统计学意义(P<0.05);对照组与研究组对比,差异无统计学意义(P>0.05)。对照组术后1、2、4、8 h镇痛评分分别为(1.11±0.32)分、(1.13±0.35)分、(1.54±0.34)分、(1.92±0.39)分,研究组分别为(1.09±0.31)分、(1.10±0.32)分、(1.52±0.35)分、(1.83±0.38)分,明显低于安慰组,差异有统计学意义(P<0.05);对照组与研究组对比,差异无统计学意义(P>0.05)。对照组术后1、2、4、8 h镇静评分分别为(2.11±0.35)分、(2.31±0.39)分、(2.40±0.43)分、(2.36±0.41)分,研究组分别为(2.06±0.36)分、(2.28±0.38)分、(2.34±0.41)分、(2.31±0.42)分,明显高于安慰组,差异有统计学意义(P<0.05);对照组与研究组对比,差异无统计学意义(P>0.05)。研究组不良反应发生率(20.00%)明显高于对照组、安慰组,差异有统计学意义(P<0.05);对照组与安慰组比较,差异无统计学意义(P>0.05)。结论 在小儿腹腔镜疝气手术超前镇痛中应用布托啡诺与地佐辛的效果显著,有助于减少患儿苏醒期躁动的发生,提高患儿术后镇痛与镇静效果,且布托啡诺的安全性更高,值得临床推荐与应用。Objective To investigate the effect of butorphanol and dezocine preemptive analgesia on postoperative analgesia in children with laparoscopic hernia surgery.Methods A total of 90 children who underwent laparoscopic hernia surgery in the hospital from July 2020 to July 2021 were conveniently selected and randomly divided into groups,including 30 cases in the placebo group,30 cases in the control group,and 30 cases in the study group.The control group was given butorphanol for preemptive analgesia,the study group was given dezocine for preemptive analgesia,and the placebo group was given normal saline for preemptive analgesia.The occurrence of agitation,analgesic effect,sedative effect,and adverse reactions in the three groups were observed and recorded,and then the observation results were compared.Results The incidence of agitation during recovery in both the control group and the study group was 6.67%,which was significantly lower than that in the placebo group,the difference was statistically significant(P<0.05).There was no statistically significant difference between the control group and the study group(P>0.05).The analgesic scores at 1 h,2 h,4 h,and 8 h after the operation in the control group were(1.11±0.32)points,(1.13±0.35)points,(1.54±0.34)points,and(1.92±0.39)points,respectively,and in the study group were(1.09±0.31)points,(1.10±0.32)points,(1.52±0.35)points,(1.83±0.38)points,which were significantly lower than the placebo group, the difference was statistically significant(P<0.05). There was no statistically significant difference between the control group and the study group (P>0.05). The scores of sedation at 1 h, 2 h, 4 h, and 8 h after operation in the control group were (2.11±0.35) points, (2.31±0.39) points, (2.40±0.43) points, and (2.36±0.41) points, respectively, and in the study group were (2.06±0.36) points, (2.28±0.38) points, (2.34±0.41) points, and (2.31±0.42) points, which were significantly higher than those in the placebo group, the difference was statistically signific

关 键 词：小儿 腹腔镜疝气手术 超前镇痛 布托啡诺 地佐辛 术后镇痛 

分 类 号：R614[医药卫生—麻醉学]