腹腔镜下子宫切除术治疗良性子宫疾病的效果及安全性  

Effect and safety of laparoscopic hysterectomy on benign uterine diseases

作　　者：郑春艳 祁彩珍 郑丽霞 曹锦慧 刘雅淑 ZHENG Chunyan;QI Caizhen;ZHENG Lixia;CAO Jinhui;LIU Yashu(Xingyuan Hospital of Yulin,Yulin 719000,China)

机构地区：[1]榆林市星元医院,陕西榆林719000

出　　处：《临床医学研究与实践》2022年第18期8-11,共4页Clinical Research and Practice

基　　金：榆林市科技计划项目(No.YF-2020-165)。

摘　　要：目的研究腹腔镜下子宫切除术治疗良性子宫疾病的效果及安全性。方法选择榆林市星元医院2016年1月至2019年12月收治的100例良性子宫疾病患者作为研究对象,按照随机抽签法将其分为对照组与观察组,每组50例。对照组采取经腹子宫切除术进行治疗,观察组实施腹腔镜下子宫切除术。比较两组的手术指标、疼痛程度、炎症因子、性激素指标[黄体生成素(LH)、卵泡刺激素(FSH)、雌二醇(E_(2))]水平及并发症发生情况。结果观察组的术中出血量少于对照组,手术时间、术后肛门首次排气时间、术后留置导管时间、住院时间均短于对照组,差异具有统计学意义(P<0.05)。观察组术后1、3、7 d的视觉模拟评分法(VAS)评分均低于对照组,差异具有统计学意义(P<0.05)。术后7 d,两组患者的血清白细胞介素-6、白细胞介素-8及C反应蛋白水平高于术前,但观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者术前、术后1个月的LH、FSH、E_(2)水平比较,差异无统计学意义(P>0.05)。观察组的术后并发症总发生率为4.00%,低于对照组的22.00%,差异具有统计学意义(P<0.05)。结论腹腔镜下子宫切除术治疗良性子宫疾病有利于减少术中出血量,缩短操作时间及住院时间,减轻术后疼痛程度和炎症反应,降低术后并发症发生率。Objective To study the effect and safety of laparoscopic hysterectomy on benign uterine diseases.Methods One hundred patients with benign uterine diseases admitted in Xingyuan Hospital of Yulin from January 2016 to December 2019 were selected as the research objects.The patients were divided into control group and observation group according to the random lottery method,with 50 cases in each group.The control group was treated with transabdominal hysterectomy,while the observation group was treated with laparoscopic hysterectomy.The operation indexes,pain degree,levels of inflammatory factors,sex hormone indexes[luteinizing hormone(LH),follicle-stimulating hormone(FSH),estradiol(E_(2))]and complications were compared between the two groups.Results The intraoperative blood loss in the observation group was less than that in the control group,the operation time,first postoperative anal exhaust time,postoperative indwelling catheter time and hospitalization time were shorter than those in the control group,and the differences were statistically significant(P<0.05).The visual analogue scale(VAS)score at 1,3 and 7 d after operation in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).At 7 d after operation,the levels of serum interleukin-6,interleukin-8 and C-reactive protein in the two groups were higher than those before operation,those in the observation group were lower than the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the levels of LH,FSH and E_(2) between the two groups before operation and at 1 month after operation(P>0.05).The total incidence of postoperative complications in the observation group was 4.00%,which was lower than 22.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic hysterectomy in the treatment of benign uterine diseases is beneficial to reduce intraoperative bleed loss,shorten operation time and hosp

关 键 词：良性子宫疾病 经腹子宫切除术 腹腔镜下子宫切除术 

分 类 号：R713.42[医药卫生—妇产科学]