血管腔内介入治疗糖尿病足的临床效果  

Clinical effect of intravascular intervention in the treatment of diabetic foot

作　　者：刘光辉 张其润 邱福轩 LIU Guanghui;ZHANG Qirun;QIU Fuxuan(No.3 Ward of General Surgery Department,Central Hospital,Jiaozuo Coal Industry(Group)Co.,Ltd,Jiaozuo 454000,China)

机构地区：[1]焦作煤业(集团)有限责任公司中央医院普通外科三区,河南焦作454000

出　　处：《临床医学研究与实践》2022年第18期48-50,共3页Clinical Research and Practice

摘　　要：目的探讨血管腔内介入治疗糖尿病足的临床效果。方法选取2019年1月至2020年1月我院收治的70例糖尿病足患者作为研究对象,根据治疗方案将其分为内科组和介入组,各35例。内科组实施常规综合治疗,介入组实施血管腔内介入治疗。比较两组的治疗效果。结果介入组的治疗总有效率高于内科组(P<0.05)。治疗后,两组的血管内皮生长因子(VEGF)水平均升高,肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)及超敏C反应蛋白(hs-CRP)水平均降低,血管内径、血流量均增大,且介入组优于内科组(P<0.05)。介入组的患肢麻木及低温完全消失时间、溃疡创口完全愈合时间、总住院时长短于内科组,住院期间换药次数少于内科组,治疗后的视觉模拟评分法(VAS)评分及1年内复发率低于内科组,治疗后的踝肱指数(ABI)高于内科组(P<0.05)。结论血管腔内介入治疗糖尿病足的效果显著,可降低炎症因子水平,改善足背血流动力学指标及临床指标。Objective To investigate the clinical effect of intravascular intervention in the treatment of diabetic foot.Methods A total of 70 patients with diabetic foot treated in our hospital from January 2019 to January 2020 were selected as the research objects.The patients were divided into internal medicine group and intervention group according to the treatment plan,with 35 cases in each group.The internal medicine group received routine comprehensive treatment,and the intervention group received intravascular intervention treatment.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the intervention group was higher than that in the internal medicine group(P<0.05).After treatment,the level of vascular endothelial growth factor(VEGF)increased,the levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and high-sensitive C-reactive protein(hs-CRP)decreased,the vessel diameter and blood flow increased in both groups,and those in the intervention group were better than the internal medicine group(P<0.05).The complete disappearance time of limb numbness and hypothermia,complete healing time of ulcer wound and total length of hospital stay in the intervention group were shorter than those in the internal medicine group,the number of dressing changes during hospitalization was less than that in the internal medicine group,the visual analogue scale(VAS)score after treatment and recurrence rate within one year were lower than those in the internal medicine group,and the ankle brachial index(ABI)after treatment was higher than that in the internal medicine group(P<0.05).Conclusion Intravascular intervention is effective in the treatment of diabetic foot,which can reduce the levels of inflammatory factors and improve the hemodynamic indexes of dorsal foot and clinical indexes.

关 键 词：糖尿病足 血管腔内介入 足背血流动力学指标 

分 类 号：R65[医药卫生—外科学]