心脏代谢指数与单纯收缩期高血压的相关性研究  

Association between cardiometabolic index and isolated systolic hypertension

作　　者：张静萍[1] 周雨芳 王畅 郭潇繁[2] 李昭[2] 周颖 于莎莎[2] 杨红梅[2] 孙英贤[2] 张莹[2] ZHANG Jing-ping;ZHOU Yu-fang;WANG Chang;GUO Xiao-fan;LI Zhao;ZHOU Ying;YU Shasha;YANG Hong-mei;SUN Ying-xian;ZHANG-Ying(Shengjing Hospital of China Medical University,Shenyang 110004,China;不详)

机构地区：[1]中国医科大学附属盛京医院,辽宁沈阳110004 [2]中国医科大学附属第一医院心血管内科,辽宁沈阳110001

出　　处：《中国实用内科杂志》2022年第5期399-403,共5页Chinese Journal of Practical Internal Medicine

基　　金：十三五国家重点研发计划(2017YFC1307600)。

摘　　要：目的了解中国东北地区人群基于2017年美国心脏病学会、美国心脏协会高血压指南新定义的单纯性收缩期高血压(ISH)患病率,并探讨心脏代谢指数与ISH的关联,为该类人群制定有针对性的防控措施提供参考依据。方法资料源于中国医科大学附属第一医院2013年分层多阶段随机抽取11678名辽宁省居民的问卷调查,及其血压、腰围、体质指数、三酰甘油等数据,采用二元logistic回归模型分析心脏代谢指数与ISH患病风险的关系。结果(1)本次调查居民中,男性的ISH患病率为16.6%,女性ISH患病率为18.7%。(2)logistic回归结果显示,在原始模型中,每增加一个心脏代谢指数SD单位,男性ISH患病风险是原来的0.693倍(95%CI 0.616~0.780);调整了年龄、性别、教育、收入、饮酒、体质指数、心脏病病史后,男性ISH风险(每增加一个心脏代谢指数SD单位)是原来的0.745倍(P<0.05),心脏代谢指数的第二百分位数和第四百分位数的ISH患病风险分别是参照组的0.629倍(95%CI 0.449~0.882)和0.508倍(95%CI 0.343~0.753),男性中ISH患病率随着心脏代谢指数的升高而逐渐下降。结论心脏代谢指数与ISH患病率在男性中呈负相关。Objective To learn about the prevalence of isolated systolic hypertension in the population of Northeast China using 2017 American College of Cardiology(ACC)/American Heart Association(AHA)hypertension guideline,and to explore the relationship between cardiometabolic index(CMI)and isolated systolic hypertension(ISH),so as to provide a reference to formulate targeted prevention and control measures for this group.Methods In 2013,11678 residents of Liaoning Province were randomly selected in First Hospital of China Medical University by a stratified and multi-stage survey to conduct a questionnaire survey,and their blood pressure,waist circumference,body mass index,triglycerides,and other data were measured.A binary Logistic regression model was used to analyze the relationship between CMI and ISH.Results(1)Among the residents in this survey,the prevalence of ISH in men was 16.6%,and the prevalence of ISH in women was 18.7%.(2)Logistic regression results showed that in the original model,the odds ratio(OR)for 1 SD increase of CMI was 0.693 times(95%CI 0.616-0.780)among male participants.The odds ratio(OR)for 1 SD increase of CMI was 0.745 times(P<0.05)after adjusting for age,gender,education,income,alcohol consumption,body mass index and heart disease in males.The risk of ISH in the second percentile and fourth percentile of CMI was 0.629 times(95%CI0.449-0.882)and 0.508 times(95%CI 0.343-0.753)respectively that of the reference group.The prevalence of isolated systolic hypertension gradually decreased with the increase of cardiometabolic index in males.Conclusion Cardiometabolic index and the prevalence of isolated systolic hypertension are negatively correlated among men.

关 键 词：单纯性收缩期高血压 心脏代谢指数 血脂水平 肥胖指标 

分 类 号：R544.1[医药卫生—心血管疾病]