开食料中添加包被丁酸钠对哺乳犊牛免疫机能和抗氧化机能的影响  

Effect of Fat-coated Sodium Butyrate in Starters on The Immune Function and Antioxidant Indexes of Preweaning Calves

作　　者：吴东霖 徐明[1] 孟庆爽[1] 王彦东 徐二华[2] 肖玲 WU Donglin;XU Ming;MENG Qingshuang;WANG Yandong;XU Erhua;XIAO Ling(College of Animal Science,Inner Mongolia Agricultural University,Inner Mongolia Hohhot 010018,China;Hangzhou King Techina Feed Co.,Ltd.,Zhejiang Hangzhou 311107,China)

机构地区：[1]内蒙古农业大学动物科学学院,内蒙古呼和浩特010018 [2]杭州康德权饲料有限公司,浙江杭州311107

出　　处：《饲料工业》2022年第11期47-50,共4页Feed Industry

基　　金：内蒙古重大专项[2020ZD0004];呼和浩特科技计划项目[2020-KJXM-GC13]。

摘　　要：文章选择不同释放速率的包被丁酸钠,研究开食料中添加包被丁酸钠对哺乳犊牛免疫和抗氧化机能的影响。试验选择出生5 d内的公犊牛40头,随机等分为4组:对照组、Z组、N组和E组。对照组不添加丁酸钠,Z组、N组和E组分别添加不包被丁酸钠、释放速率快和慢的包被丁酸钠。结果显示:与对照组相比,Z组、N组和E组显著提高血清免疫球蛋白G含量(P<0.05),显著降低白细胞介素1β和肿瘤坏死因子α含量(P<0.05),不影响肠道黏膜分泌型免疫球蛋白含量(P>0.05);Z组、N组和E组显著提高超氧化物歧化酶、谷胱甘肽过氧化物酶活性和总抗氧化能力(P<0.05),E组最高;显著降低丙二醛、一氧化氮和皮质醇浓度(P<0.05),E组最低;过氧化氢酶活性差异不显著(P>0.05)。综上,丁酸钠可提高哺乳犊牛免疫和抗氧化机能,释放速率慢的包被丁酸钠效果最佳。Coated sodium butyrate was selected to study the effects of coated sodium butyrate with different release rates on immune and antioxidant function of preweaning calves.Forty healthy Holstein calves within five days after birth were divided into four groups:control,group Z,N and E.Group Z was added0.3% uncoated sodium butyrate in starters.Group N and E were added 0.3% coated sodium butyrate with fast and slow release rate in the starter respectivery.The experimental data showed that:①sodium butyrate(Group Z,N and E) increased the serum IgG content(P<0.05),decreased serum IL-1β and TNF-α content,and had no significant effect on mucosal sIgA content in the large and small intestine of calves(P>0.05);②sodium butyrate(Group Z,N and E) increased the serum SOD,GSH-Px and T-AOC of calves,decreased the concentrations of MDA,NO and cortisol(P<0.05),and had no significant effect on CAT(P>0.05).Based on the above results,adding sodium butyrate into the starters could improve the immune function and antioxidant ability of preweaning calves,and coated sodium butyrate with slow release rate was the best.

关 键 词：丁酸钠 包被 免疫机能 抗氧化机能 哺乳犊牛 

分 类 号：S816.32[农业科学—饲料科学]