鼠脑的复折射率研究  

Research on the Complex Refractive Index of Mouse Brain

作　　者：刘诗可 邓志超[1] 李建威[2] 王槿[1] 黄宁宁 崔芮铭 张倩南 梅剑春 周文远[1] 张春平[1] 叶青[1] 田建国[1] Liu Shike;Deng Zhichao;Li Jianwei;Wang Jin;Huang Ningning;Cui Ruiming;Zhang Qiannan;Mei Jianchun;Zhou Wenyuan;Zhang Chunping;Ye Qing;Tian Jianguo(School of Physics,Nankai University,Tianjin 300071,China;Division of Optics,National Institute of Metrology,Beijing 100029,China;Advanced Technology Institute,Nankai University,Tianjin 300071,China)

机构地区：[1]南开大学物理科学学院,天津300071 [2]中国计量科学研究院光学与激光计量科学研究所,北京100029 [3]南开大学现代应用技术研究院,天津300071

出　　处：《南开大学学报（自然科学版）》2022年第2期41-44,共4页Acta Scientiarum Naturalium Universitatis Nankaiensis

基　　金：国家重点研发计划(2018YFF0212105);国家自然科学基金(61475078,31527801)。

摘　　要：采用全内反射法对鼠脑冠状切片组织黑质区进行测量,基于简化为双层模型的梯度复折射率多层模型,拟合得到鼠脑样品复折射率为1.3760和0.0040.与菲尼尔公式相比,梯度复折射率多层模型拟合得到的相关系数更高,样品折射率和消光系数随着穿透深度增加而变大,在临界角处的入射光穿透深度为216 nm.The refractive index of the substantia nigra area of the mouse brain coronal section was measured with the total internal reflection method. Based on the two-layers model which is simplified from the gradient complex refractive index multilayered model, the complex refractive index of the rat brain samples is 1.370 6 and 0.004 0. The correlation coefficient obtained by the gradient complex refractive index multilayered model is higher than Fresnel’s formula. The refraction index and extinction coefficient of sample become bigger as penetration depth increases, and the penetration depth of the incident light at critical angel is 216 nm.

关 键 词：生物组织 复折射率 梯度复折射率多层模型 全内反射法 

分 类 号：R318[医药卫生—生物医学工程]