宜昌城区尿钾、尿钠、尿肌酐参考区间的建立及比较  

Establishment and comparison of reference intervals of urinary potassium,urinary sodium and urinary creatinine in urban areas of Yichang city

作　　者：徐珊 姚倩兰 孙凤英[1] 杜胤[1] XU Shan;YAO Qianlan;SUN Fengying;DU Yin(the Health Management Service Center,Yichang Center for Disease Control and Prevention,Yichang,Hubei 443000,China)

机构地区：[1]宜昌市疾病预防控制中心健康管理服务中心,湖北宜昌443000

出　　处：《检验医学与临床》2022年第12期1632-1634,1638,共4页Laboratory Medicine and Clinic

摘　　要：目的初步建立宜昌城区晨尿的尿钾、尿钠、尿肌酐参考区间。方法在城区3所小学内共选定300个的家庭,两次收集晨尿共计1380份,使用全自动生化分析仪和电解质分析仪对其尿钾、尿钠、尿肌酐进行定量分析,并将结果进行统计分析。结果尿钾、尿钠、尿肌酐水平均呈偏态分布,以95%CI来建立参考区间,尿钾参考区间为29.3(11.0~80.3)mmol/L、尿钠参考区间为101.5(47.1~191.5)mmol/L、尿肌酐参考区间为10992.0(3644.8~26168.6)μmol/L,成年人和青少年的尿钾、尿肌酐水平差异均有统计学意义(P<0.05),成年人群中男性和女性的尿肌酐水平差异有统计学意义(P<0.05)。结论青少年与成年人的晨尿尿钾、尿肌酐参考区间存在差异,应按照年龄及性别初步建立适合该地区晨尿检测项目的参考区间。Objective To preliminarily establish the reference intervals of potassium,sodium and creatinine in morning urine in urban areas of Yichang.Methods A total of 1380 morning urine samples were collected twice from 300 families in 3 primary schools in urban areas,potassium,sodium and creatinine in urine were quantitatively analyzed by automatic biochemical analyzer and electrolyte analyzer,and the results were statistically analyzed.Results The levels of potassium,sodium and creatinine in urine were skewed,and the reference interval was established with 95%CI.The reference interval of urinary potassium was 29.3(11.0—80.3)mmol/L,the reference interval of urinary sodium was 101.5(47.1—191.5)mmol/L,the reference interval of urinary creatinine was 10992.0(3644.8—26168.6)μmol/L.There were significant differences in urinary potassium and creatinine levels between adults and adolescents(P<0.05).There was significant difference in urinary creatinine level between male and female in adult population(P<0.05).Conclusion There are differences in the reference intervals of potassium and creatinine in morning urine between adolescents and adults.Therefore,a reference interval suitable for morning urine detection in this area should be preliminarily established according to age and gender.

关 键 词：晨尿 尿钾 尿钠 尿肌酐 参考区间 

分 类 号：R446.1[医药卫生—诊断学]