EMT导致不孕病因及其ART助孕策略的研究新进展  

New progress in research on the causes of EMT-induced infertility and its ART strategy

作　　者：宋姗姿 邹琳 SONG Shanzi;ZOU Lin(Guangdong Medical University,Guangdong,Zhanjiang 524000,China;Department of Reproductive Medicine,Affiliated Hospital of Guangdong Medical University,Guangdong,Zhanjiang 524001,China)

机构地区：[1]广东医科大学,广东湛江524000 [2]广东医科大学附属医院生殖医学科,广东湛江524001

出　　处：《中国医药科学》2022年第10期34-37,共4页China Medicine And Pharmacy

基　　金：广东省省级科技计划项目(2015A080803009)。

摘　　要：子宫内膜异位症(EMT)是一种雌激素依赖性的妇科常见疾病。虽然是一个良性疾病,但有恶性侵袭和种植生长能力。在EMT患者中,合并不孕症的有40%~50%,而EMT导致不孕症的病因尚未明确。其影响因素主要有盆腔解剖结构的异常、盆腔内环境的改变等。目前临床上治疗EMT所致不孕症以辅助生殖技术(ART)为主,主要有人工授精(AI)、体外受精-胚胎移植(IVF-ET)助孕治疗,以IVF-ET为主,超长方案是IVF-ET的主要促排卵方案。目前,治疗卵巢子宫内膜异位囊肿(OEC)所致不孕症面对的问题主要是如何保护患者的卵巢储备功能,这也将指导其他未来治疗的发展方向。以下主要综合论述EMT不孕与ART相关研究新进展。Endometriosis(EMT)is a common estrogen-dependent gynecological disease.Benign disease as it is,it has the ability of malignant invasion and seeding growth.40%-50%of EMT patients have infertility,and the cause of EMT-induced infertility is not yet clear.The influencing factors are mainly abnormal pelvic anatomy and changes in the pelvic environment.At present,assisted reproductive technology(ART)is the main clinical treatment of EMT-induced infertility,mainly including assisted fertility treatments,such as artificial insemination(AI)and in vitro fertilization-embryo transfer(IVF-ET)(chief method),and the ultra-long plan is the main ovulation promotion plan of IVF-ET.At present,the main problem in the treatment of infertility caused by ovarian endometriotic cyst(OEC)is how to protect the patient’s ovarian reserve function,which will also guide the development direction of its future treatment.The following mainly discusses the new progress of EMT infertility and ART related research.

关 键 词：子宫内膜异位症 卵巢子宫内膜异位囊肿 不孕症 辅助生殖技术 体外受精-胚胎移植 

分 类 号：R271.14[医药卫生—中医妇科学]