基于“厥阴欲解时”理论评价乌梅丸治疗夜间哮喘的临床疗效  

Clinical Effects of Wumei Pills in the Treatment of Nocturnal Asthma Based on the Theory of"The Time of Jueyin Disease Easily Attacking"

作　　者：史锁芳[1] 胡珀 胡念芬[1] SHI Suofang;HU Po;HU Nianfen(Affiliated Hospital of Nanjing University of TCM,Nanjing 210029,China;Nanjing University of Chinese Medicine)

机构地区：[1]南京中医药大学附属医院,江苏南京210029 [2]南京中医药大学

出　　处：《西部中医药》2022年第6期103-106,共4页Western Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(82004304);南京中医药大学附属医院课题(Y19015)。

摘　　要：目的:探究乌梅丸治疗夜间哮喘的临床疗效。方法:选择108例夜间哮喘患者,采用乌梅丸治疗,治疗4周后比较患者各观察点临床疗效、证候总积分、夜间证候积分、临床控制水平积分、肺功能、免疫球蛋白E(immunoglobulin E,IgE)水平及安全性。结果:乌梅丸治疗夜间哮喘总有效率为93.5%(101/108);治疗后证候积分及夜间证候积分明显降低,差异有统计学意义(P<0.05);治疗后部分患者的肺功能得到改善,但IgE水平在2~4周内未见明显改善。结论:乌梅丸可有效控制夜间哮喘患者的急性发作症状,改善肺功能,控制哮喘病情,且安全性较高。Objective:To explore clinical effects of Wumei pills in the treatment of nocturnal asthma.Methods:All 108 patients with nocturnal asthma were chosen and treated by Wumei pills,to compare clinical effects,total integrals of TCM syndrome,the scores of night syndrome,the scores of clinical control level,pulmonary function,the levels of IgE and safety in the patients at observation points after four weeks of treatment.Results:Total effective rate of Wumei pills in the treatment of nocturnal asthma was 93.5%(101/108),syndrome integrals,and the scores of night syndrome lowered notably after treatment,the difference was statistically significant(P<0.05)pulmonary function improved,while the levels of IgE were not improved significantly within two to four weeks after treatment.Conclusion:Wumei pills could effectively control the symptoms in patients at the time of acute attack,improve pulmonary function,control the disease conditions of asthma with higher safety.

关 键 词：哮喘 夜间 乌梅丸 厥阴欲解时 临床评价 

分 类 号：R256.12[医药卫生—中医内科学]