血府逐瘀汤加减治疗老年稳定型心绞痛并焦虑抑郁状态30例疗效观察  

Curative effect observation of treatment with modified Xuefu Zhuyu decoction in the 30 cases elderly patients with stable angina pectoris complicated with anxious or depressed state

作　　者：杜卫甫[1] 程晓昱[1] 姚淮芳[1] DU Weifu;CHENG Xiaoyu;YAO Huaifang(Center for Clinical Research of Geriatric Cardiology Diseases,The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei,Anhui230031,China)

机构地区：[1]安徽中医药大学第一附属医院老年病中心心内科,安徽合肥230031

出　　处：《安徽医药》2022年第7期1462-1465,共4页Anhui Medical and Pharmaceutical Journal

基　　金：安徽省卫生和计划生育委员会中医药领军人才培养对象专项项目(中医药发展秘[2018]23号)。

摘　　要：目的 观察血府逐瘀汤加减治疗老年稳定型心绞痛的“双心”(即心脏疾病合并心理疾病)疗效。方法 选取安徽中医药大学第一附属医院老年病心内科2019年1—12月住院的老年稳定型心绞痛病人60例,分为对照组和观察组各30例。对照组给予常规药物治疗,观察组在常规治疗基础上给予血府逐瘀汤加减治疗,两组均以4周为1个疗程。治疗前后观察临床症状发作情况、心电图,采用广泛性焦虑量表(GAD-7)进行焦虑评定,同时记录不良反应情况。结果 治疗4周后,观察组的临床总有效率为86.67%,高于对照组的73.33%(P<0.05),心电图改善总有效率观察组为93.33%,优于对照组的73.33%(P<0.05),治疗后焦虑发生率观察组为16.7%,低于对照组的46.7%,广泛性焦虑量表评分观察组为(4.03±1.85)分,低于对照组的(6.32±3.04)分,均差异有统计学意义(P<0.05)。结论 血府逐瘀汤加减能够显著提高老年稳定型心绞痛的临床疗效,可明显改善病人心电图,降低焦虑发生率以及GAD-7评分,发挥了“双心”治疗效应。Objective patients with stable angina pectoris.Methods A total of 60 elderly patients with stable angina pectoris who underwent cardiology treatment in the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2019 to December 2019 were selected.The patients were randomly assigned into control group(n=30) and observation group(n=30).The control group was given the conventional medications,while the bservation group was given modified Xuefu Zhuyu decoction on the basis of conventional therapy,4weeks as a course.Clinical TCM symptoms were observed,the electrocardiogram was determined and the patients were given anxiety reviews by using generalized anxiety disorder-7(GAD-7) before and after treatment,and adverse reactions were recorded.Results After four weeks of the treatment,the clinical total effective rate in observation group was 86.67%,which was higher than the 73.33% of control group(P<0.05).The total effective rate of electrocardiograph improvement in the observation group was 93.33%,which was better than the 73.33% of control group(P<0.05).The occurrence rate of anxiety after treatment in the observation group was 16.7%,which was lower than the 46.7% of control group,and the score of GAD-7 in the observation group was(4.03±1.85) scores,which was lower than the control group [(6.32±3.04) scores],there were statistical differences between patients with observation group and control group(P<0.05).Conclusions tients with stable angina pectoris,and it may improve obviously the patients’ electrocardiogram.It can reduce the occurrence rate of anxiety and score of GAD-7,which can get the effect of "psycho-cardiology".

关 键 词：心绞痛 稳定型 焦虑 血府逐瘀汤 老年人 “双心”医学 

分 类 号：R259[医药卫生—中西医结合]