应用叶天士“肝-胃”理论防治化疗恶心呕吐研究  

Application of Ye Tian-shi's"Liver-Stomach"Theory in Prevention and Treatment of Chemotherapy Induced Nausea and Vomiting

作　　者：潘彦君 姜苗[1,2] 翟昌明 刘振梅 PAN Yan-jun;JIANG Miao;ZHAI Chang-ming;LIU Zhen-mei(Dongzhimen Hospital of Beijing University of traditional Chinese Medicine,Beijing 100700)

机构地区：[1]北京中医药大学东直门医院,北京100700 [2]北京中医药大学生命科学学院,北京100029

出　　处：《河北中医药学报》2022年第3期15-17,52,共4页Journal of Hebei Traditional Chinese Medicine and Pharmacology

基　　金：北京中医药大学资助项目:No.BUCM-2021-JS-KF-002。

摘　　要：化疗所致恶心呕吐(CINV)是化疗最常见的不良反应之一。笔者通过临床观察及文献研究发现,胃气上逆为CINV发病的基本病机,肝胃功能失和在其中发挥着重要作用。清代医家叶天士在其《临证指南医案》中多有肝胃不和导致脾胃-肝胆系疾病的论述,后人称之为“肝-胃”学术思想。本文即通过对CINV病机及叶氏“肝-胃”学术思想的分析与梳理,探讨泄肝安胃法在CINV防治中的应用。Chemotherapy induced nausea and vomiting(CINV)is one of the most common adverse reactions of chemotherapy.Through clinical observation and literature research,the author found that the basic pathogenesis of CINV is reverse ascending of stomach qi,in which the liver and stomach dysfunction plays an important role.Ye Tian-shi,a physician in the Qing Dynasty,often discussed in his Case Records as a Guide to Clinical Practice(Lin Zheng Zhi Nan Yi An)that liver-stomach disharmony led to the diseases of spleen-stomach and liver-gallbladder system,which was later called the"liver-stomach"thought.This article discusses the application of Xiegan Anwei method in the prevention and treatment of CINV by analyzing the pathogenesis of CINV and Ye's academic thought of"liver-stomach".

关 键 词：叶天士 化疗 恶心呕吐 “肝-胃”理论 痞满 胃气上逆 肝胃同治 泄肝安胃法 

分 类 号：R256.31[医药卫生—中医内科学]