MSCT三期增强扫描联合5种血清肿瘤标志物检测在肺癌诊断及临床病理分型中的应用价值  

Application Value of MSCT Three-Phase Enhanced Scan Combined with the Detection of Five Serum Tumor Markers in the Diagnosis of Lung Cancer and Clinical Pathological Typing

作　　者：曹栋栋 吕伟 王宪章 孙艳 CAO Dong-dong;LYU Wei;WANG Xian-zhang;SUN Yan(Department of Imaging,Xinyi City People's Hospital,Jiangsu Province,Xuzhou 221400,Jiangsu Province,China)

机构地区：[1]江苏省新沂市人民医院医学影像科,江苏徐州221400

出　　处：《中国CT和MRI杂志》2022年第7期64-66,共3页Chinese Journal of CT and MRI

摘　　要：目的分析多层螺旋CT(MSCT)三期增强扫描联合5种血清肿瘤标志物检测在肺癌诊断及临床病理分型中的应用价值。方法回顾性分析2018年6月至2019年12月于我院就诊治疗的94例肺癌患者的临床及影像学资料,另选取60例健康体检者,总结不同检查方式对肺癌诊断的准确率以及相关影像学表现,并比较不同人群相关指标水平。结果肺癌患者CA153、CA125、NSE、.CEA和CYFRA21-1水平均显著高于健康体检者(P<005);MSCT检查联合CA153、CA125、NSE、CEA和CYFRA21-1检测对肺癌的诊断符合率.均显著高于MSCT及5种肿瘤标志物单项检查者(P<005)。结论CA153、CA125、NSE、CEA和CYFRA21-1水平在肺癌患者中显著上升,而MSCT增强扫描检查可清晰显出病灶大小、形态及位置,二者联合对肺癌的诊断价值更高,更值得临床推广使用。Objective To analyze the application value of multi-slice spiral CT(MsCT) three-phase enhanced scan combined with the detection of five serum tumor markers in the diagnosis of lung cancer and clinical pathological typing. Methods The clinical and imaging data of 94 patients with lung cancer treated in our hospital from June 2018 to December 2019 were retrospectively analyzed. Another 60 healthy medical examiners were selected, and the accuracy of different examinations in the diagnosis of lung cancer and related imaging performance were summarized, and the relevant indicator levels in different people were compared. Results The levels of CA153, CA125, Ns E, CEA, and CYFRA21-1 in patients with lung cancer were significantly higher than those in healthy subjects(P<0.05). The diagnostic accuracy of Ms CT combined with CA153, CA125, Ns E, CEA and CYFRA21-1 tests for lung cancer were significantly higher than those of Ms CT and 5 tumor markers alone(P<0.05). Conclusion The levels of CA153, CA125, Ns E, CEA and CYFRA21-1 significantly increased in patients with lung cancer, and Ms CT enhanced scans can clearly show the size, shape and location of the lesions. The combination of them has higher diagnostic value for lung cancer and it is more worthy of clinical promotion.

关 键 词：多层螺旋CT 血清肿瘤标志物 肺癌 影像学特征 诊断价值 

分 类 号：R445.3[医药卫生—影像医学与核医学] R734.2[医药卫生—诊断学]