Versatile Ti_(3)C_(2)T_(x)MXene for free-radical scavenging  

作　　者：Jiang Liu Wei Lu Xifeng Lu Lu Zhang Haifeng Dong Yingchun Li 

机构地区：[1]Flexible Printed Electronics Technology Center and School of Science,Harbin Institute of Technology(Shenzhen),Shenzhen 518055,China [2]Department of Physiology,Health Science Center,Shenzhen University,Shenzhen 518055,China [3]Marshall Laboratory of Biomedical Engineering,Research Center for Biosensor and Nanotheranostic,School of Biomedical Engineering,Shenzhen University,Shenzhen 518055,China

出　　处：《Nano Research》2022年第3期2558-2566,共9页纳米研究（英文版）

基　　金：the Key Program of Natural Science Foundation of Shenzhen(No.JCYJ20200109113410174);the National Natural Science Foundation of China(No.81973280);the Key Technique Improvement of Xinjiang Licorice Planting and Quality Control of Xinjiang Production&Construction Corps(No.2018AB012);Guangdong Province Covid-19 Pandemic Control Research Fund(No.2020KZDZX1223)。

摘　　要：MXene,as an emerging two-dimensional(2D)material with ultrathin structure and fascinating physiochemical properties,has been widely explored in broad applications.Versatile functions of MXenes are continuously explored.This work presents distinctive feature of MXene-Ti_(3)C_(2)T_(x)nanosheets for free-radical(FRs)scavenging that never reported before.We demonstrated the mechanism and equation in regard to the reaction between Ti_(3)C_(2)T_(x)and H_(2)O_(2),which was applied to design colorimetric H_(2)O_(2)strip assay with good performance.The good FRs scavenging capability of Ti_(3)C_(2)T_(x),including a series of reactive oxygen species(ROS)and reactive nitrogen species(RNS),was systemically confirmed.The antioxidation capability of Ti_(3)C_(2)T_(x)for protecting cells from oxidative damage was demonstrated using the oxidative damage model of alpha mouse liver 12(AML-12)cells.This original work provides huge opportunities for MXenes in FR-related biomedical applications.

关 键 词：MXene hydrogen peroxide colorimetric sensor reactive oxygen species anti-oxidative damage 

分 类 号：TB30[一般工业技术—材料科学与工程]