畜禽消化道细菌群体感应及相关调控技术研究进展  

Research Progress and Related Regulation Technology on Bacterial Quorum Sensing in the Gastro-intestinal Tract of Livestock and Poultry

作　　者：郭海康 万发春 沈维军[1] 王祚 GUO Haikang;WAN Fachun;SHEN Weijun;WANG Zuo(College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China)

机构地区：[1]湖南农业大学动物科学技术学院,长沙410128

出　　处：《畜牧兽医学报》2022年第6期1678-1688,共11页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：湖南省教育厅优秀青年项目(19B257);湖南省自然科学基金青年基金(2019JJ50279);国家肉牛牦牛产业技术体系(CARS-37);国家自然科学基金面上项目(31772633)。

摘　　要：群体感应是一种微生物细胞间的通讯机制,它在细菌毒力因子表达、生物发光、孢子形成、生物膜形成等方面起关键调控作用。近年来陆续发现畜禽消化道菌群同样存在有群体感应现象。鉴于消化道菌群对畜禽消化、生理代谢、免疫功能等的重要作用,针对畜禽消化道细菌群体感应进行研究及调控对于提高畜禽生产水平及保障畜禽健康等均具有重要的意义。本文简述了细菌群体感应的分类及作用,介绍了国内外学者对不同畜禽消化道中细菌群体感应的研究发现,归纳并总结了当前细菌群体感应相关的调控手段及其可能机制,以期为畜禽养殖中消化道细菌群体感应的研究及相关应用提供参考依据。Quorum sensing(QS)is a microbial cell-to-cell communication mechanism that plays a key regulatory role in bacterial virulence factor expression,bioluminescence,spore formation,and biofilm formation.In recent years,researchers have found that QS also exists in the gastro-intestinal tract of livestock and poultry.In view of the significant role of gastro-intestinal microflora in the digestion,physiological metabolisms,and immune functions of animals,research and regulation of gastro-intestinal bacterial QS is of great significance in guaranteeing health and improving production performance.In this paper,the classifications and effects of bacterial QS,and the research findings of gastro-intestinal bacterial QS in different domestic animals was reviewed,and the relevant regulation and potential mechanisms of QS were also introduced,in order to provide reference for the research and application of bacterial QS in livestock and poultry industry.

关 键 词：群体感应 细菌 畜禽消化道 畜禽生产 

分 类 号：S852.6[农业科学—基础兽医学]