委陵菜属植物的化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Potentilla

作　　者：吴嘉 张在其 余黄合[1] 黄费炳 陈柱梁 储玲玲 李斌[1] 王炜[1] WU Jia;ZHANG Zai-qi;YU Huang-he;HUANG Fei-bing;CHEN Zhu-liang;CHU Ling-ling;LI Bin;WANG Wei(Traditional Chinese Medicine and Ethnomedicine Innovation&Development International Laboratory,Hunan University of Chinese Medicine,Changsha 410208,China;Hunan Provincial Key Laboratory of Dong Medicine,Hunan University of Medicine,Huaihua 418000,China)

机构地区：[1]湖南中医药大学中医药民族医药国际联合实验室,湖南长沙410208 [2]湖南医药学院侗医药研究湖南省重点实验室,湖南怀化418000

出　　处：《中国中药杂志》2022年第6期1509-1538,共30页China Journal of Chinese Materia Medica

基　　金：侗医药研究湖南省重点实验室项目(2015TP1020-04);侗医药研究湖南省重点实验室平台建设项目(2017CT5025);侗医药研究湖南省重点实验室开放课题(YS2019YFE012440)。

摘　　要：蔷薇科委陵菜属Potentilla植物全球现存200~500种,约有90余种在我国广泛分布,且多为民族用药。笔者统计目前已从该属植物中共分离并鉴定367个化合物,涵盖萜类、黄酮类、酚酸类、鞣质类、苯丙素类等,药理作用主要涉及抗氧化、降糖、抗炎、抗肿瘤、心血管系统保护、神经保护、保肝等。该文系统综述了国内外委陵菜属植物的化学成分和药理活性研究进展,为其进一步深入研究和临床应用提供科学依据。There are 200-500 species of Potentilla(Rosaceae)worldwide,among which 90 species are widely distributed in China and have a long history of ethnic medicinal use.According to our statistics,a total of 367 compounds have been isolated and identified from plants of this genus,including terpenoids,flavonoids,phenolic acids,tannins,and phenylpropanoids.The medicinal materials made from these plants mainly have antioxidative,blood sugar-lowering,anti-inflammatory,anti-tumor,cardiovascular system-protecting,neuroprotective,and hepatoprotective activities.This study systematically reviews the research progress on chemical constituents and pharmacological activities of Potentilla plants to provide a basis for further research and clinical application.

关 键 词：委陵菜属 化学成分 药理活性 综述 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]